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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Dehydroxyfluorafinil

    Aliases: Fiendz, Modafiendz, N-methylbisfluoromodafinil

    Summary TheDrug.Wiki TripSit PsychonautWiki

    N-Methyl-4,4'-difluoro-modafinil (also known as N-Methylbisfluoromodafinil, Dehydroxyfluorafinil, and Modafiendz) is an obscure nootropic of the benzhydryl class with no history of research. Although it is closely related on a structural level to adrafinil and modafinil, neither a pharmacological nor a safety-profile similarity should be assumed.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-150mg 150-200mg 200mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 30-60 min 2-4 hrs 2-4 hrs 2-6 hrs 4.5-9 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 4.8
    Moderate+ 5/10

    Strong focus and anxiety/jitters with mild stimulation, low euphoria

    Stimulation / Energy ×3
    5
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    2
    motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement memory enhancement motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    9
    anxiety increased heart rate vasoconstriction sweating

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 7d Half tolerance 3d Baseline ~14d

    Patterns extrapolated from modafinil‑class anecdotal use; daily use for 1–2 weeks often blunts effects, with partial reversal after 3–5 days off and near‑baseline after 2–4 weeks. Data quality is anecdotal, individual variability is high.

    Cross-Tolerances

    Effects TheDrug.Wiki

    Positive
    • Stimulation
    Negative
    • Increased heart rate
    • Headaches
    • Nausea
    • Headache
    • Vasoconstriction
    • Sweating
    • Diarrhea
    • Insomnia
    Neutral
    • Body odor alteration
    Positive
    • Wakefulness
    • Focus enhancement
    • Motivation enhancement
    • Memory enhancement
    • Emotion enhancement
    Negative
    • Dizziness
    • Anxiety
    • Irritability
    Neutral
    • Thought acceleration
    • Time distortion
    Positive
    • Increased Music Appreciation
    • Increased music appreciation
    • Increased libido
    • Libido enhancement
    Negative
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    • Photophobia
    • Appetite Suppression
    Neutral
    • Spontaneous physical sensations

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