Diclazepam
Aliases: Chlorodiazepam, 2'-chloro-diazepam
Summary
Diclazepam is an unscheduled research chemical benzodiazepine not approved for medical use in most countries. It is structurally related to diazepam but approximately 10 times more potent in animal studies. Its long half-life of approximately 42 hours and active metabolites (delorazepam, lorazepam, lormetazepam) lead to accumulation with repeated use and prolonged effects lasting days.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 0.5-1mg | 1-3mg | 3-4mg | 4mg+ |
Benzo Equivalence Calculator
| Substance | Equivalent Dose | Potency |
|---|
⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 10-90 min | 1-3 hrs | 2-6 hrs | 4-12 hrs | 7.2-22.5 hrs |
Effect Profile
21 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Validated against 21 Erowid trip reports
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiolysis, cognitive impairment, euphoria, and sedation
Tolerance
Tolerance Decay
Benzodiazepine tolerance to hypnotic/sedative effects can develop within days to weeks of regular use and decays slowly over weeks after cessation; cross-tolerance exists across benzodiazepines and is partial with Zโdrugs. Values are heuristic for planning safer spacing between uses; strong inter-individual variability. Data quality: mixed guidance from public-health profiles and community experience rather than controlled trials.
Cross-Tolerances
Effects
Aggregated from 21 Erowid experience reports