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    Disclaimer
    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    โš  Benzodiazepines can cause physical dependence with regular use. Withdrawal can be life-threatening. Never combine with opioids or alcohol.

    Diclazepam

    Aliases: Chlorodiazepam, 2'-chloro-diazepam

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Diclazepam is an unscheduled research chemical benzodiazepine not approved for medical use in most countries. It is structurally related to diazepam but approximately 10 times more potent in animal studies. Its long half-life of approximately 42 hours and active metabolites (delorazepam, lorazepam, lormetazepam) lead to accumulation with repeated use and prolonged effects lasting days.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 0.5-1mg 1-3mg 3-4mg 4mg+
    Light Common Strong Heavy

    Benzo Equivalence Calculator

    mg
    1.0 mg Diclazepam
    =
    โ€” mg Diazepam

    ⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 10-90 min 1-3 hrs 2-6 hrs 4-12 hrs 48-48 hrs 7.2-22.5 hrs

    Effect Profile

    21 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 21 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Benzodiazepine 8.3
    Intense 8/10

    Strong anxiolysis, cognitive impairment, euphoria, and sedation

    Anxiolysis ×3
    10
    anxiety suppression anxiolytic muscle relaxation muscle relaxant emotion suppression
    Sedation / Relaxation ×2
    9
    sedation muscle relaxation
    Motor / Cognitive Impairment ×1
    10
    motor control loss amnesia delusions of sobriety
    Euphoria / Mood Lift ×1
    10
    physical euphoria disinhibition

    Tolerance

    Build-up develops over 1โ€“4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
    Reset weeks to months depending on half-life and duration of use; taper recommended

    Tolerance Decay

    Full tolerance 7d Half tolerance 14d Baseline ~30d

    Benzodiazepine tolerance to hypnotic/sedative effects can develop within days to weeks of regular use and decays slowly over weeks after cessation; cross-tolerance exists across benzodiazepines and is partial with Zโ€‘drugs. Values are heuristic for planning safer spacing between uses; strong inter-individual variability. Data quality: mixed guidance from public-health profiles and community experience rather than controlled trials.

    Effects Erowid

    Aggregated from 21 Erowid experience reports

    Positive Effects 4

    Anxiety Suppression 52.4% 70%
    Euphoria 42.9% 70%
    Sedation 42.9% 70%
    Stimulation 19.0% 70%

    Adverse Effects 2

    Memory Suppression 28.6% 70%
    Motor Impairment 23.8% 70%

    Combinations TripSit

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