Diclazepam
Aliases: Chlorodiazepam, 2'-chloro-diazepam
Categories
Summary
Diclazepam is an unscheduled research chemical benzodiazepine not approved for medical use in most countries. It is structurally related to diazepam but approximately 10 times more potent in animal studies. Its long half-life of approximately 42 hours and active metabolites (delorazepam, lorazepam, lormetazepam) lead to accumulation with repeated use and prolonged effects lasting days. Delusions of sobriety are common at higher doses, where users feel sober despite significant impairment. Volumetric dosing is strongly recommended due to the substance's high potency.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 0.5-1mg | 1-3mg | 3-4mg | 4mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 10-90 min | 1-3 hrs | 2-6 hrs | 4-12 hrs | 48 hrs | 480-0 min |
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Effects
Positive
- Muscle relaxation
- Anxiolytic
- Muscle Relaxant
- Physical euphoria
Negative
- Respiratory depression
- Motor impairment
- Sedation
- Sedative
- Dystaxia
- Hypnotic
Positive
- Anxiety suppression
Negative
- Amnesia
- Motor control loss
- Thought deceleration
- Emotion suppression
- Delusions of sobriety
- Compulsive redosing
- Analysis suppression
- Delusions
- Dizziness
- Information processing suppression
Positive
Negative
- Disinhibition
- Decreased Libido
- Acuity Suppression
- Visual acuity suppression
- Appetite suppression
- Acuity suppression
- Dulled perception
- Hallucinations
- Perception of bodily heaviness
- Appetite fluctuation