Summary
A powerful opioid of equivalent strength to morphine, rarely seen outside of medical environments. Often used to treat severe pain where morphine is contraindicated. Usually found in combination with the antihistamine Cyclizine, which potentiates it.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 3-5mg | 5-10mg | 10-20mg | 20mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | After Effects | Total |
|---|---|---|---|---|
| Oral | 15-30 min | 3.0-6.0 hrs | 1.0-12.0 hrs | 180-0 min |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Effects
Positive
- Analgesia
- Stimulation
- Physical euphoria
Negative
- Dry Mouth
- Increased heart rate
- Nausea
- Itchiness
- Relaxant
- Pupil constriction
- Sedation
Positive
- Euphoria
- Mood lift
- Reduced anxiety
- Cognitive euphoria
- Anxiety suppression
Negative
- Constipation
- Compulsive redosing
- Anxiety
- Thought deceleration
- Time distortion
Positive
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
Negative
- Disinhibition
- Light sensitivity
- Appetite suppression
- Dehydration
- Double vision
- Dulled perception