DPP-26
Aliases: Db-900274, Dipipanone sulfone analogue
Categories
Summary
DPP-26 is the sulfone analogue of dipipanone, structurally related to IC-26 (methiodone, the sulfone analogue of methadone). Early user reports describe it as having faster onset and shorter duration than methadone, with notable euphoria. Vendor specifications and limited reports suggest approximately 0.4x morphine potency (roughly 25 mg DPP-26 equivalent to 10 mg morphine). No peer-reviewed pharmacokinetic or toxicological data exist; all parameters are extrapolated from dipipanone studies and anecdotal reports. Sample verification by third-party analysis is strongly advised due to analog confusion and inconsistent naming in the research chemical market.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-45 min | 30-60 min | 1-3 hrs | 4-6 hrs | 12 hrs |
| Insufflated | 5-15 min | 15-30 min | 1-3 hrs | 3-5 hrs | 8 hrs |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Effects
Positive
- Physical euphoria
- Pain relief
- Muscle relaxation
- Stimulation
Negative
- Respiratory depression
- Nausea
- Increased heart rate
- Sedation
- Itchiness
- Pupil constriction
Positive
- Cognitive euphoria
- Anxiety suppression
- Reduced anxiety
- Euphoria
Negative
- Constipation
- Compulsive redosing
- Anxiety
- Thought deceleration
- Dizziness
- Time distortion
Positive
- Increased music appreciation
- Increased libido
- Tactile enhancement
- Color enhancement
Negative
- Disinhibition
- Light sensitivity
- Appetite suppression
- Dehydration
- Double vision
- Dulled perception