Summary
Ephedrine is a naturally occurring alkaloid found in Ephedra species. It is used medically as a bronchodilator, decongestant, and to treat hypotension. Structurally similar to amphetamines but less potent. Regulated in many countries due to its use as a precursor in illicit methamphetamine synthesis. Side effects include increased heart rate, hypertension, anxiety, insomnia, and urinary retention.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-20mg | 20-30mg | 30-50mg | 50mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|
| Oral | 20-90 min | 1-2 hrs | 2-4 hrs | 2-4 hrs | 0 min |
| Insufflated | 5-15 min | 30-60 min | 1-2 hrs | 2-4 hrs | 0 min |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Increased heart rate
- Increased blood pressure
- Insomnia
- Restlessness
- Dry mouth
- Nausea
- Pupil dilation
- Sedation
Positive
- Cognitive euphoria
- Memory enhancement
- Alertness enhancement
- Euphoria
- Wakefulness
Negative
- Anxiety
- Dizziness
- Confusion
- Talkativeness
- Time distortion
Positive
- Visual acuity enhancement
- Auditory enhancement
Negative
- Appetite suppression
- Light sensitivity
- Drifting
- Internal hallucination
- Auditory hallucinations
- Internal hallucinations
- Perception of increased weight
- Auditory distortion