Escaline Stats & Data

Escaline was first described in the scientific literature by George S. Grace in 1934. It was subsequently synthesized and reported by F. Benington and colleagues in 1954. The compound was later re-examined in the laboratory of David E. Nichols, who prepared a series of mescaline analogues including escaline, proscaline, and isoproscaline, publishing their findings in 1977. The effects of escaline in humans were documented by Alexander Shulgin in his 1991 book PiHKAL: A Chemical Love Story. The name "escaline" derives from an etymological play on words related to its chemical structure. The central oxygen of mescaline bears a methyl group (one carbon), with the prefix "methyl" stemming from the Greek word "methy" meaning wine. When this methyl group is replaced with an ethyl group (two carbons), the natural linguistic extension transforms "mescaline" to "escaline." While this relationship is etymologically appealing, it carries no botanical significance—escaline has no known natural source. The coincidence that mescaline, methyl, and methoxy all begin with the letter "M" is simply fortuitous.

From 7 individual dose entries