Escaline
Aliases: E
Summary
Escaline is a research chemical with very limited human use history and no formal toxicology studies. It is a Schedule I controlled substance in the United States (DEA #7930), and also controlled in Germany, Japan, Sweden, Switzerland, and the UK. In comparison to mescaline, escaline is approximately 5-8 times more potent but produces significantly more intense negative physical side effects, less insightful cognitive effects, and less complex visual effects.
Perspectives
“This drug was better than I had expected it to be, but still was not very much. It seems to light a fire in my mind, generating improved and accelerated cognition, leaving the dynamo of the brain feeling burnt out afterwards. Sensory effects are minor.”
“This is a powerful and complex intoxicant—I could not have coordinated any rational muscular activity. I could not walk; I could not tie my shoe-laces. There is analgesia and an incoordination that I cannot shake. My menstrual flow started a bit ahead of time, but it was light.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 30-50mg | 50-100mg | 100-150mg | 150mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 1-2 hrs | 30-60 min | 5-6 hrs | 2-4 hrs | 8-12 hrs |
Effect Profile
2 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong visuals, headspace, auditory effects, and body load
Tolerance
Tolerance Decay
Effects
- Stimulation
- Mental/physical stimulation
- Spontaneous tactile sensations
- Pupil Dilation
- Increased Heart Rate
- Muscle Tension
- Vasoconstriction
- Physical Discomfort
- Restlessness
- Sweating/chills
- Insomnia
- Muscle spasms
- Nausea
- Temperature Dysregulation
- Decreased appetite
- Thought Connectivity
- Novelty Enhancement
- Conceptual Thinking
- Immersion Enhancement
- Increased Sense Of Humor
- Mindfulness
- Wakefulness
- Euphoria
- Empathy
- Insight
- Emotion enhancement
- Memory Suppression
- Confusion
- Delusions
- Thought disorganization
- Thought loops
- Thought Acceleration
- Time Distortion
- Personal Bias Suppression
- Change in perception
- Ego softening
- Perspective alterations
- Enhanced Color
- Increased Music Appreciation
- Tracers
- Colour Shifting
- Brightened colour
- Enhanced tactile sensation
- Acuity enhancement
- Auditory enhancement
- Bodily control enhancement
- Colour enhancement
- Pattern recognition enhancement
- Tactile enhancement
- Drifting
- After Images
- Symmetrical Texture Repetition
- Scenery Slicing
- Closed/Open eye visuals
- Auditory distortion
- Auditory hallucinations
- Autonomous entities
- External hallucinations
- Internal hallucinations
Combinations
Trip Reports
PiHKAL / TiHKAL
“This is a powerful and complex intoxicant—I could not have coordinated any rational muscular activity. I could not walk; I could not tie my shoe-laces. There is analgesia and an incoordination that I cannot shake. My menstrual flow started a bit ahead of time, but it was light.”