Home
    Disclaimer
    ← Back to Ether
    Ether molecular structure

    Ether Stats & Data

    Depressant Dissociative
    Sweet vitriol diethyl-ether Diethyl ether
    NPS DataHub
    MW184.49
    FormulaC3H2ClF5O
    CAS13838-16-9
    IUPAC2-Chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane
    SMILESFC(F)OC(F)(F)C(F)Cl
    InChIKeyJPGQOUSTVILISH-UHFFFAOYSA-N
    Psychoactive Class Depressant / Dissociative

    Pharmacology

    DrugBank

    Mechanism of Action

    The mechanism of action by which .... ethyl ether produce/s/ reversible loss of consciousness is still unclear. Anesthesia can be produced by a wide variety of chemical agents, ranging from inert rare gases to steriodal molecules. This apparent lack of specificity, together with the observation that general anesthesia can be reversed by high pressure, poses a unique pharmacological problem. Most theories concern interaction of anesthetics with either membrane lipids or hydrophobic regions of sp

    Metabolism

    It has been estimated that about 8-10% of absorbed ethyl ether is metabolized in the body whereas the remainder is excreted unchanged through the lungs. Ethyl ether is metabolized to ethanol and acetaldehyde by the inducible hepatic microsomal enzyme system, a cytochrome P450-containing monooxygenase system. Ethanol and acetaldehyde are rapidly oxidized to acetate, and the acetate subsequently enters the 2-carbon pool of intermediary metabolism.

    Effect Profile

    Curated + 72 Reports
    Dissociative 1.6

    Strong mania with low motor impairment and dissociative depth

    Dissociative Depth×3
    12.5
    Mania / Compulsion×1
    101.3
    Insight / Novel Thought×2
    0
    Motor / Sensory Impairment×1
    23.1
    Catalog Erowid
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Ether

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Experience Report Analysis

    Erowid
    72 Reports
    1996–2025 Date Range
    10 With Age Data
    22 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 72 experience reports (72 Erowid)

    72 Reports
    22 Effects Detected
    12 Positive
    5 Adverse
    5 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 12

    Anxiety Suppression 33.3% 70%
    Euphoria 23.6% 70%
    Color Enhancement 13.9% 70%
    Focus Enhancement 13.9% 70%
    Music Enhancement 12.5% 70%
    Introspection 11.1% 70%
    Tactile Enhancement 9.7% 70%
    Empathy 8.3% 70%
    Stimulation 6.9% 70%
    Sedation 6.9% 70%
    Body High 5.6% 70%
    Pain Relief 4.2% 70%

    Adverse Effects 5

    Confusion 19.4% 70%
    Nausea 13.9% 70%
    Memory Suppression 9.7% 70%
    Motor Impairment 9.7% 70%
    Headache 6.9% 70%

    Real-World Dose Distribution

    62K Doses

    From 30 individual dose entries

    Form / Preparation

    Most common forms and preparations reported

    Redose Patterns

    Redosing behavior across 49 reports

    4.1% Redosed
    1.0 Avg Doses
    Read full reports on Erowid →
    ← Back to Ether