Ether Stats & Data
CCOCCRTZKZFJDLAIYFH-UHFFFAOYSA-NPharmacology
DrugBankMechanism of Action
The mechanism of action by which .... ethyl ether produce/s/ reversible loss of consciousness is still unclear. Anesthesia can be produced by a wide variety of chemical agents, ranging from inert rare gases to steriodal molecules. This apparent lack of specificity, together with the observation that general anesthesia can be reversed by high pressure, poses a unique pharmacological problem. Most theories concern interaction of anesthetics with either membrane lipids or hydrophobic regions of sp
Metabolism
It has been estimated that about 8-10% of absorbed ethyl ether is metabolized in the body whereas the remainder is excreted unchanged through the lungs. Ethyl ether is metabolized to ethanol and acetaldehyde by the inducible hepatic microsomal enzyme system, a cytochrome P450-containing monooxygenase system. Ethanol and acetaldehyde are rapidly oxidized to acetate, and the acetate subsequently enters the 2-carbon pool of intermediary metabolism.
This section covers risks general risks for both medical and nonmedical inhalants. For specific risks with nonmedical inhalants, see Toxicity and harm potential for toxic inhalants It is strongly recommended that one use harm reduction practices when using this class of substances. Both medical and nonmedical inhalants should be avoided by:
LD50
LD50: 996 mg/kg (Intravenous, Mouse) (L1327)LD50: 2420 mg/kg (Intraperitoneal, Mouse) (L1327)LD50: 1213 mg/kg (Oral, Rat) (A681)
Carcinogenicity
No indication of carcinogenicity to humans (not listed by IARC).
Addiction & dependence
The chronic use of many inhalants can be considered moderately addictive with a high potential for abuse and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and withdrawal effects may occur if a person suddenly stops their usage.
Effect Profile
Curated + 72 ReportsStrong mania with low motor impairment and dissociative depth
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 72 experience reports (72 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 12
Adverse Effects 5
Real-World Dose Distribution
62K DosesFrom 30 individual dose entries
Form / Preparation
Most common forms and preparations reported
Redose Patterns
Redosing behavior across 49 reports