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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Ethketamine Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 2 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • classified Research-chemical

    Aliases: Nek, N-ethyl-norketamine, n-ethylnorketamine

    Depressant Dissociative Research-chemical

    Summary TripSit

    Ethketamine is a research chemical with properties similar to ketamine. While ketamine is a dissociative anesthetic producing hallucinogenic and sedative effects, recreational users have reported euphoria and dissociation when using NENK.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 15-40mg 40-90mg 90-160mg 160mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects
    Oral 15-30 min 2-4 hrs 1-3 hrs

    Effect Profile

    1 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 1.7
    Light 2/10

    Strong mania with low dissociative depth and motor impairment

    Dissociative Depth ×3
    1
    amnesia
    ⚠ Mania / Compulsion ×1
    10
    compulsive redosing disinhibition stimulation euphoria
    Insight / Novel Thought ×2
    0
    ⚠ Motor / Sensory Impairment ×1
    1
    double vision
    Based on reports from:
    Bluelight Big & Dandy Thread Erowid Experience Reports
    View methodology →

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Ethketamine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "Ethketamine (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    Ethketamine
    Unit
    mg
    Description 
    Ethketamine
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): light 15-40 · common 40-90 · strong 90-160 · heavy 160+

Oral duration: onset 15-30m · peak 2-4h · after-effects 1-3h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 65 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset days to weeks depending on duration of use

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects

    Positive
    • Stimulation
    • Physical euphoria
    • Muscle relaxation
    Negative
    • Motor impairment
    • Increased heart rate
    • Nausea
    • Respiratory depression
    • Vasoconstriction
    • Teeth grinding
    Neutral
    • Sedation
    Positive
    • Reduced anxiety
    • Cognitive euphoria
    • Euphoria
    • Anxiety suppression
    Negative
    • Compulsive redosing
    • Anxiety
    • Thought deceleration
    • Dizziness
    • Amnesia
    Neutral
    • Time distortion
    Positive
    • Increased music appreciation
    • Increased libido
    • Tactile enhancement
    • Color enhancement
    Negative
    • Disinhibition
    • Light sensitivity
    • Appetite suppression
    • Dehydration
    • Double vision
    Neutral
    • Dulled perception

    Combinations TripSit

    Cross-Check Ethketamine with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 1 report 1 neutral visit
    Dissapointed And Bummed Out On This One neutral exp #98173

    N-ethyl-norketamine sucks [Erowid Note: A substance(s) in this report might be identified incorrectly. Erowid reviewers question the author's identification of the drug described.

    hyperobjects · N-Ethylnorketamine · 5 mg / 50 mg / 20 mg / 325 mg

    Bluelight Reference Guide Bluelight

    The Big & Dandy N-Ethyl-Norketamine Thread

    What is the experience any of you have with this compared to K?

    Read full thread on Bluelight →
    Ethketamine's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 Bluelight 📖 PsychonautWiki