Summary
Flubrotizolam is an extremely potent thienotriazolodiazepine with active doses in the sub-milligram range. It is metabolized primarily by CYP3A4 enzymes. Volumetric dosing is strongly recommended due to potency. Avoid compulsive redosing and never combine with other depressants.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 10-30 min | 30-60 min | 1-3 hrs | 2-4 hrs | 6-12 hrs |
Tolerance
Build-up
develops over 1–4 weeks of daily use; hypnotic tolerance faster than anxiolytic tolerance
Reset
weeks to months depending on half-life and duration of use; taper recommended
Effects
Positive
- Muscle relaxation
- Physical euphoria
- Anxiolytic
- Muscle Relaxant
Negative
- Motor impairment
- Respiratory depression
- Sedation
- Sedative
- Dystaxia
- Hypnotic
Positive
- Anxiety suppression
- Cognitive euphoria
Negative
- Amnesia
- Motor control loss
- Emotion suppression
- Delusions of sobriety
- Compulsive redosing
- Thought deceleration
- Delusions
- Dizziness
Positive
- Increased libido
- Appetite enhancement
- Increased music appreciation
Negative
- Disinhibition
- Visual acuity suppression
- Acuity suppression
- Dehydration
- Light sensitivity
- Dulled perception
- Perception of bodily heaviness