Fludiazepam Stats & Data
ROYOYTLGDLIGBX-UHFFFAOYSA-NPharmacology
DrugBankDescription
Fludiazepam is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. It is a scheduled drug in the U.S., but is approved for use in Japan.
Mechanism of Action
Fludiazepam has similar action to diazepam, but binds with four times more affinity to benzodiazepine receptors than diazepam.
Pharmacodynamics
Fludiazepam is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Fludiazepam accumulates primarily in the cortex and thalamus.
Indication
Used for the short-term treatment of anxiety disorders.
Fludiazepam has similar action to diazepam, but binds with four times more affinity to benzodiazepine receptors than diazepam.
Carcinogenicity
No indication of carcinogenicity to humans (not listed by IARC).
Toxicity (DrugBank)
Symptoms of overdose include drowsiness, weakness, nausea, dizziness, abdominal pain, cerebral oedema and renal tubular necrosis, hyperglycaemia and hypoglycaemia, liver damage, encephalopathy, coma and death.
Effect Profile
CuratedStrong anxiolysis and euphoria with moderate cognitive impairment, mild sedation
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.