Flupirtine
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- duration data present
- dose data not in PW/TripSit (unverifiable)
- 2 corroborating sources
- duration data present
- dose data not in PW/TripSit (unverifiable)
Aliases: Pruf, W-2964, D-9998, Awegal, Efiret
Summary
Flupirtine is a pyridine derivative that is in clinical use as a nonopioid analgesic. It was approved for the treatment of pain in 1984 in Europe. It is not approved for use in the U.S. or Canada, but is currently in phase II trials for the treatment of fibromyalgia.
Dose Information
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 30-60 min | 30-60 min | 1-2 hrs | 4-6 hrs |
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Pain Relief
- Muscle Relaxation
- Physical euphoria
- Pain relief
- Fatigue
- Motor impairment
- Respiratory depression
- Nausea
- Sedation
- Itchiness
- Reduced anxiety
- Anxiety suppression
- Cognitive euphoria
- Dream potentiation
- Focus enhancement
- Motivation enhancement
- Euphoria
- Dizziness
- Drowsiness
- Constipation
- Increased music appreciation
- Appetite suppression
- Double vision
- Light sensitivity
- Disinhibition
- Acuity suppression
- Visual acuity suppression
- Dulled perception
- Internal hallucination
- Perception of bodily heaviness
Helpful Links
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