Summary
Gabapentinoids, also known as ฮฑ2ฮด ligands, are a relatively small chemical class of psychoactive substances derived from gamma-aminobutyric acid (GABA).[citation needed] Members of this class include gabapentin, F-phenibut, phenibut and pregabalin.
Tolerance
Build-up
develops over 1โ4 weeks of regular use
Reset
days to weeks depending on duration of use
Effects
Positive
- Physical euphoria
- Muscle relaxation
- Anxiolytic
Negative
- Motor impairment
- Nausea
- Respiratory depression
- Sedation
- Sedative
- Dystaxia
- Itchiness
Positive
- Reduced anxiety
- Anxiety suppression
- Cognitive euphoria
- Euphoria
Negative
- Dizziness
- Compulsive redosing
- Amnesia
- Thought deceleration
- Motor control loss
- Constipation
Positive
- Increased music appreciation
- Increased libido
Negative
- Disinhibition
- Appetite suppression
- Dehydration
- Light sensitivity
- Double vision
- Acuity suppression
- Dulled perception
- Internal hallucinations