Summary
GHB has an extremely steep dose-response curve; the difference between a recreational and dangerous dose can be as little as 1-2 grams. Doses above 10 grams are associated with high risk of death. Never combine with alcohol or other depressants. Always measure doses precisely using accurate equipment and wait at least 2-4 hours between doses. GHB is used medically as sodium oxybate (Xyrem) for narcolepsy treatment.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral BA ~25-30% | 0.5-1.5g | 1-2.5g | 2-3.5g | 3.5-5g+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Oral | 4-30 min | 10-19 min | 45-90 min | 15-30 min | 2.0-4.0 hrs | 1.5-2.5 hrs |
Tolerance
Build-up
develops rapidly within days of regular around-the-clock dosing
Reset
3–7 days for acute tolerance
Cross-tolerance
Effects
Positive
- Muscle relaxation
- Physical euphoria
- Anxiolytic
- Pain relief
Negative
- Nausea
- Respiratory depression
- Sedation
- Sleepiness
- Dystaxia
- Sedative
Positive
- Euphoria
- Anxiety suppression
- Cognitive euphoria
- Empathy enhancement
- Sociability enhancement
Negative
- Motor control loss
- Dizziness
- Memory suppression
- Amnesia
- Thought deceleration
Positive
- Increased libido
- Increased music appreciation
- Appetite enhancement
- Increased Libido
Negative
- Disinhibition
- Double vision
- Dehydration
- Spatial Disorientation
- Dulled perception
- Optical sliding