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    Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    Glaucine Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 1 source
    • 1 ROA with full dose ladder
    • duration data present
    • 19 combo interactions documented
    • classified Tentative

    Summary TripSit

    An alkaloid that is found in several different scpecies in the Papaveraceae family. It has antiinflammatory and antitussive effects. Can also be referred to as Yellow Horned Poppy.

    Perspectives

    “This is by far one of the worst drugs I have taken. Has little to no redeeming factors. Absolutely nothing.”

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 50-100mg 100-150mg 150-200mg 200mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 45-90 min 6-8 hrs 1-8 hrs 6-8 hrs

    Effect Profile

    8 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 3.9
    Moderate 4/10

    Moderate euphoria with mild itching/nausea, low sedation

    Euphoria / Warmth ×3
    6
    euphoria cognitive euphoria
    Analgesia ×2
    0
    Sedation / Relaxation ×1
    3
    sedation
    Itching / Nausea ×1
    4
    nausea

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d

    Effects Erowid

    Aggregated from 8 Erowid experience reports

    Positive Effects 5

    Euphoria 62.5% 70%
    Sedation 62.5% 70%
    Color Enhancement 50.0% 70%
    Focus Enhancement 37.5% 70%
    Anxiety Suppression 37.5% 70%

    Adverse Effects 1

    Nausea 37.5% 70%

    Combinations TripSit

    Cross-Check Glaucine with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 4 reports 4 neutral visit
    A Quality and Lasting Experience neutral exp #100488

    Background: I acquired a gram of Glaucine HBr purely by chance. I purchased 2 packs of HBW seeds, and the seller threw in the gift of 1 gram of Glaucine (it was a mystery gift, I didn't know what I was getting until it arrived).

    doomdoom · 200 mg oral
    Slightly Undervalued neutral exp #105736

    In Ukraine where I live Glaucine is a legal, anti-tussive, over-the-counter (!) drug. It is available in a form of dragee containing 40 mg of Glaucine hydrobromide each and produced by “Sopharma”, Bulgary. Thanks to Hatter's report which helped with choosing the dosage.

    Krakowoshch · 160 mg oral
    Comfortably Comfortable Numbness neutral exp #79784

    The substance in question is an extract from Yellow Horned Poppy labeled “Glaucine hbr. 99% isolate, Origin Denmark.” I purchased this product from a reliable Canadian Entheogen supplier and I have had a variety of experiences with the drug, all of which have been positive.

    Hatter · 180 mg oral
    A Miserable Substance neutral exp #96066

    I acquired 1 gram of Glaucine HBr from an online source. Doses were tried ranging from 100mg to 500mg, with the substance dissolved in a glass of water. It tastes disgustingly bitter. Effects come on extremely quickly, say 5 minutes and resemble a very weak opiate high with a stimulant edge.

    GeoffTipps · oral
    Bluelight 2 threads 2 neutral visit
    Glaucine 200 Mg Oral First Time Manufactured Depression neutral

    Age: 21 Weight: 125 lbs Dosage: 200 mg oral in gel cap Setting: My apartment T0:00-Dosed. My roommate and one of my closest friends moved out today, I feel sad about his leaving because I am very bad at dealing with change. The decision to take this drug was rash and uncalculated.

    scraped 2026-03-14
    Glaucine Hbr 150 Mg Went Through Almost 2 Grams In The Course Of A Month neutral

    I recently gave Glaucine, a dissociative derived from the yellow horned poppy a spin around the block-- quite a number of times, and it exceeded my expectations. As you would expect from a poppy based dissociative, the feeling is rather like DXM, but with fewer unpleasant side effects, although some people have experie...

    scraped 2026-03-14

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