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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    GVL Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • duration data present
    • classified Research-chemical
    • dose data not in PW/TripSit (unverifiable)

    Aliases: Tranquili-g, 4-pentanolide, 4-methylbutyrolactone, Gamma-methyl-gamma-butyrolactone

    Summary dose.wiki

    GVL has a density of approximately 1.05 g/mL, meaning 1 mL contains roughly 1050 mg of neat GVL. Animal studies indicate GBL is 5-7 times more potent than GVL, with human anecdotal reports aligning with typical single doses of 3-7 mL and binge totals exceeding 40 mL. Subjectively less euphoric but significantly longer-acting than GBL/GHB, with effects that plateau rather than peak sharply.

    Dose Information dose.wiki

    ROA Threshold
    Oral 1mL

    Only a threshold dose is documented for this substance โ€” the smallest amount with a noticeable effect. There is no published light/common/strong ladder to show above it.

    Onset, Duration & After-effects dose.wiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 20-40 min 30-60 min 1-3 hrs 2-4 hrs 4-8 hrs 3.83-8.67 hrs

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track GVL there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    GVL
    Unit
    ml
    Description
    GVL
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (ml): threshold 1mL
    
    Oral duration: onset 20-40m ยท come-up 0.5-1h ยท peak 1-3h ยท offset 2-4h ยท total 3.83-8.67h ยท after-effects 4-8h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over 1โ€“4 weeks of regular use
    Reset days to weeks depending on duration of use

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects Erowid

    Aggregated from 6 Erowid experience reports

    Positive Effects 2

    Sedation 50.0% 70%
    Anxiety Suppression 50.0% 70%

    Adverse Effects 0

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 3 reports 2 neutral 1 cautionary visit
    Bad Tasting Money Wasting cautionary exp #19202

    It's been a long day, I've had sinus problems all day, and been somewhat zonked from a combination of not not feeling good and taking sinus medicine. Around 11:00 I had taken a Tavist-D which was making me feel pretty drained. 2:00 Mix 5 ml of GVL solution into a shot glass of water. I have never tried GHB or GVL.

    Purist Love · 5.0 ml oral
    Completely Devoid of Any Pleasure neutral exp #24393

    I recently ordered several bottles of Tranquili-G, much to my disappointment. I started with the suggested dose of 1 teaspoon (1/6 ounce) with absolutely no effect after over an hour. I then took successively larger doses with no effect.

    Metatron's Cube · 2.5 oz oral
    Initial Impressions neutral exp #10480

    Well, a couple of days ago I posted a message to alt.drugs.ghb asking about Tranquilli-G. It arrived today; I took about 2.5mL after working from 5:30a.m til' 2:00p.m. Before I took it I was feeling agitated achy, and tired. It took about 20 min.

    Shed · 2.5 ml oral
    Bluelight 1 thread 1 neutral visit
    Gvl First Time Bad Tasting Money Wasting neutral

    It's been a long day, I've had sinus problems all day, and been somewhat zonked from a combination of not not feeling good and taking sinus medicine. Around 11:00 I had taken a Tavist-D which was making me feel pretty drained. 2:00 Mix 5 ml of GVL solution into a shot glass of water. I have never tried GHB or GVL.

    scraped 2026-03-14

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