Halazepam
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 17 combo interactions documented
- PubChem toxicity data
Aliases: Paxipam, Alapryl, Pacinone
Summary
Halazepam is a trifluoromethyl derivative of nordazepam (desmethyldiazepam) with anxiolytic, anticonvulsant, sedative, and muscle relaxant properties. It is metabolized into pharmacologically active desmethyldiazepam with a half-life of 30-100 hours, contributing to prolonged effects and accumulation with repeated use. Halazepam was marketed as having lower toxicity and less tendency to cause paradoxical hostility than diazepam, though it was withdrawn from the US market in 2009 due to poor sales.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-20mg | 20-40mg | 40-80mg | 80mg+ |
Benzo Equivalence Calculator
| Substance | Equivalent Dose | Potency |
|---|
⚠ These are approximate equivalences for educational and cross-tapering reference. Individual response, tolerance, and half-life differences mean actual equivalence varies. Always consult a healthcare provider for tapering guidance.
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-60 min | 1-2 hrs | 1-3 hrs | 6-12 hrs | 8-14 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiolysis, cognitive impairment, and euphoria with mild sedation
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Sedative and anticonvulsant effects exhibit rapid tolerance with repeated dosing over days to weeks, similar to other benzodiazepines. Cross-tolerance is substantial across benzodiazepines and extends partially to other GABAergic sedatives (alcohol, barbiturates, Z-drugs). Tolerance generally recedes gradually over weeks to months of abstinence; individual variability is large. Data quality is limited; values are heuristic to support harm reduction, not precise pharmacometrics.
Cross-Tolerances
Effects
- Muscle relaxation
- Physical euphoria
- Anxiolytic
- Muscle Relaxant
- Respiratory depression
- Motor impairment
- Sedation
- Sedative
- Dystaxia
- Hypnotic
- Anxiety suppression
- Cognitive euphoria
- Motor control loss
- Thought deceleration
- Emotion suppression
- Memory suppression
- Amnesia
- Dizziness
- Compulsive redosing
- Delusions of sobriety
- Increased libido
- Appetite enhancement
- Disinhibition
- Acuity suppression
- Visual acuity suppression
- Decreased Libido
- Acuity Suppression
- Double vision
- Dulled perception
- Perception of bodily heaviness
Combinations
Cross-Check Halazepam with another substancePill Identifiers
Helpful Links
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