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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Hexedrone

    Aliases: Hex, Macp, Alpha-methylamino-caprophenone

    Stimulant Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Hexedrone is a synthetic stimulant cathinone with limited research and an extremely short history of human use. It is less potent than pentedrone and N-ethylhexedrone. Users should exercise extreme caution due to insufficient toxicology data and potential cardiovascular strain.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 50-70mg 70-100mg 100-125mg 125mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 15-30 min 1-2 hrs 1-2 hrs 1-12 hrs 2.2-4.5 hrs
    Insufflated 5-15 min 30-90 min 1-2 hrs 1-12 hrs 1.6-3.8 hrs

    Effect Profile

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 5.1
    Moderate+ 5/10

    Strong anxiety/jitters and focus with moderate euphoria, low stimulation

    Stimulation / Energy ×3
    3
    stimulation
    Euphoria / Mood Lift ×2
    7
    euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    9
    focus enhancement analysis enhancement thought acceleration motivation enhancement
    ⚠ Anxiety / Jitters ×1
    10
    anxiety increased heart rate teeth grinding vasoconstriction
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Hexedrone
    View methodology →

    Tolerance

    Build-up develops rapidly, often within a single session; compulsive redosing common
    Reset a few days for acute tolerance

    Tolerance Decay

    Full tolerance 1h Half tolerance 4d Baseline ~5d

    Effects TheDrug.Wiki

    Positive
    • Stimulation
    • Spontaneous tactile sensations
    Negative
    • Increased heart rate
    • Vasoconstriction
    • Teeth grinding
    • Temporary erectile dysfunction
    • Insomnia
    • Pupil dilation
    • Nausea
    Neutral
    • Sedation
    Positive
    • Euphoria
    • Focus enhancement
    • Analysis enhancement
    • Motivation enhancement
    • Cognitive euphoria
    Negative
    • Compulsive redosing
    • Anxiety
    Neutral
    • Thought acceleration
    • Time distortion
    • Ego inflation
    Positive
    • Increased music appreciation
    • Color enhancement
    • Tactile enhancement
    • Brightened colour
    Negative
    • Disinhibition
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    Neutral
    • Dulled perception
    • Drifting

    Combinations TripSit

    Hexedrone's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 TripSit 📖 PsychonautWiki