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    Hexen molecular structure

    Hexen Stats & Data

    Stimulant Research-chemical
    Neh Ethyl-hexedrone N-ethylhexedrone hex-en n-ethyl-hexedrone
    PubChem CID 134822125
    NPS DataHub
    MW219.33
    FormulaC14H21NO
    IUPAC2-(ethylamino)-1-phenylhexan-1-one
    SMILESCCCCC(NCC)C(=O)c1ccccc1
    InChIKeyCWNKMHIETKEBCA-UHFFFAOYSA-N
    Phenethylamines; Cathinones; 2020/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2021/1. Von 2-Phenethylamin abgeleitete Verbindungen; 2022/1. Von 2-Phenethylamin abgeleitete Verbindungen
    Chemical Class Cathinone
    Psychoactive Class Stimulant

    Interaction Warnings

    ⚠ stimulants

    Ethyl-Hexedrone can be potentially dangerous in combination with other stimulants as it can increase one's heart rate and blood pressure to dangerous levels.

    ⚠ mdma

    The neurotoxic effects of MDMA may be increased when combined with amphetamine and other stimulants.

    ⚠ cocaine

    This combination may increase strain on the heart.

    Pharmacology

    DrugBank

    Toxicity

    PsychonautWiki

    The toxicity and long-term health effects of recreational N-ethylhexedrone use do not seem to have been studied in any scientific context and the exact toxic dosage is unknown. This is because N-ethylhexedrone has a very brief history of human usage. Early anecdotal reports from those who have tried N-ethylhexedrone suggests that there do not seem to be any negative health effects attributed to simply trying it at low to moderate doses by itself and using it in a sparing and controlled fashion (but nothing can be completely guaranteed). Some users have reported N-ethylhexedrone to be caustic to the nasal membrane when it is insufflated. A toxicology screening indicated that measured with yeast and SH-SY5Y cells, N-Ethylhexedrone seems to be the most toxic among the five cathionones tested.

    Effect Profile

    Curated + 13 Reports
    Stimulant 4.1

    Strong anxiety/jitters with moderate stimulation and euphoria

    Stimulation / Energy×3
    7
    Euphoria / Mood Lift×2
    6
    Focus / Productivity×2
    0
    Anxiety / Jitters×1
    10
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Hexen The Drug Users Bible Hexen

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1h Half tolerance 7d Baseline ~14d

    Experience Report Analysis

    Erowid
    13 Reports
    2015–2024 Date Range
    13 With Age Data
    13 Effects Detected

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 13 experience reports (13 Erowid)

    13 Reports
    13 Effects Detected
    8 Positive
    4 Adverse
    1 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Positive Effects 8

    Focus Enhancement 76.9% 70%
    Stimulation 69.2% 70%
    Euphoria 46.2% 70%
    Music Enhancement 38.5% 70%
    Tactile Enhancement 30.8% 70%
    Body High 30.8% 70%
    Empathy 30.8% 70%
    Color Enhancement 23.1% 70%

    Adverse Effects 4

    Anxiety 46.2% 70%
    Jaw Clenching 38.5% 70%
    Nausea 23.1% 70%
    Confusion 23.1% 70%

    Real-World Dose Distribution

    62K Doses

    From 14 individual dose entries

    Insufflated (n=11)

    Median: 20.0mg 25th: 10.0mg 75th: 22.5mg 90th: 37.0mg
    mg/kg median: 0.284 mg/kg 75th: 0.367

    Form / Preparation

    Most common forms and preparations reported

    Redose Patterns

    Redosing behavior across 12 reports

    50.0% Redosed
    2.1 Avg Doses
    50m Median Interval
    Read full reports on Erowid →
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