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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    HOT-2 Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 1 source
    • 1 ROA with full dose ladder
    • duration data present
    • 18 combo interactions documented
    • classified Tentative
    • classified Research-chemical

    Aliases: hot2

    Summary TripSit

    A rather rare psychedelic phenylethylamine that is the hydroxylated version and prodrug for 2C-T-2.

    Perspectives

    “Tastes OK. Some activity noticed in 30 minutes. Very smooth rise with no body load for next two hours. At that time I noted some visuals. Very pleasant. The bright spots in the painting over the fireplace seemed to be moving backwards (as if the clouds were moving in the painting). Upon concentrating on any item, there was perceptual movement with a little flowing aspect. The visuals were never all that strong, but could not be turned off during the peak. At hour three there was still some shimmering, and it was hard to focus when reading. Additionally, there was difficulty concentrating (some mental confusion). The material seemed to allow erotic actions; there was no problem about obtaining an erection. I ate very well, some crazy dips, as well as a fabulous cake. A very gentle down trend and I became close to baseline by 6 or 7 p.m. I had no trouble driving. The dosage was good for me. I did not want more or less.”

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 10-12mg 12-15mg 15-20mg 20mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 20-40 min 5-12 hrs 1-12 hrs 5-12 hrs

    Effect Profile

    1 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 3.1
    Light+ 3/10

    Mild visuals with low body load and headspace

    Visual Intensity ×3
    4
    color enhancement brightened colour visual distortions
    Headspace Depth ×3
    2
    confusion time distortion
    Auditory Effects ×1
    0
    Body Load / Somatic Effects ×1
    3
    muscle tension increased heart rate

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track HOT-2 there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    ⬇ Download import file Import this file as custom substances and you get "HOT-2 (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.
    Name
    HOT-2
    Unit
    mg
    Description
    HOT-2
    Source: SubstanceSearch (substancesearch.com)
    
    Oral dose (mg): threshold 8 ยท light 10-12 ยท common 12-15 ยท strong 15-20 ยท heavy 20+
    
    Oral duration: onset 20-40m ยท peak 5-12h ยท total 5-12h ยท after-effects 1-12h
    
    Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 13.5 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops rapidly after a single use
    Reset 7โ€“14 days for baseline

    Tolerance Decay

    Full tolerance 1h Half tolerance 10d Baseline ~14d

    Effects TripSit

    Positive
    • Mental/physical stimulation
    • Stimulation
    Negative
    • Pupil dilation
    • Restlessness
    • Sweating/chills
    • Muscle tension
    • Insomnia
    • Increased heart rate
    Neutral
    • Decreased appetite
    • Sedation
    Positive
    • Euphoria
    • Empathy
    • Insight
    • Cognitive euphoria
    • Wakefulness
    Negative
    • Confusion
    • Anxiety
    Neutral
    • Change in perception
    • Ego softening
    • Time distortion
    Positive
    • Brightened colour
    • Enhanced tactile sensation
    • Color enhancement
    • Increased music appreciation
    Negative
    • Light sensitivity
    • Disinhibition
    • Appetite suppression
    • Dehydration
    Neutral
    • Closed/Open eye visuals
    • Visual distortions

    Combinations TripSit

    Cross-Check HOT-2 with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

    Erowid 1 report 1 positive visit
    Compared to 2C-T-2 positive exp #78825

    The original substance I had was 2c-t-2, which I put into conditions which led to the creation of the substance HOT-2. It was a long process, which I will not detail in this report, as I am a chemist and private researcher.

    MadScientist · 12 mg oral

    PiHKAL / TiHKAL Shulgin

    PiHKAL #87: HOT-2

    “Tastes OK. Some activity noticed in 30 minutes. Very smooth rise with no body load for next two hours. At that time I noted some visuals. Very pleasant. The bright spots in the painting over the fireplace seemed to be moving backwards (as if the clouds were moving in the painting). Upon concentrating on any item, there was perceptual movement with a little flowing aspect. The visuals were never all that strong, but could not be turned off during the peak. At hour three there was still some shimmering, and it was hard to focus when reading. Additionally, there was difficulty concentrating (some mental confusion). The material seemed to allow erotic actions; there was no problem about obtaining an erection. I ate very well, some crazy dips, as well as a fabulous cake. A very gentle down trend and I became close to baseline by 6 or 7 p.m. I had no trouble driving. The dosage was good for me. I did not want more or less.”

    โ€” Alexander Shulgin, PiHKAL (with 12 mg)

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