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    Ibogaine

    Aliases: Iboga, Endabuse, Nih 10567

    Depressant Dissociative Psychedelic Opioid

    Summary TheDrug.Wiki TripSit PsychonautWiki

    Ibogaine is a powerful alkaloid with unique psychedelic and dissociative properties used clinically for addiction treatment but carries significant cardiac risks including QT prolongation and arrhythmias. Medical supervision with cardiac monitoring is essential due to serious potential complications including death. It produces a two-phase experience: an initial visionary phase with intense visual phenomena lasting 4-8 hours, followed by a prolonged introspective phase.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral BA ~40% - 15-22mg/kgofbodyweight - -
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Peak Offset After Effects Total
    Oral 1-3 hrs 4-8 hrs 8-24 hrs 24-72 hrs 24-30 hrs

    Effect Profile

    63 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 46 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 8.5
    Intense 8/10

    Strong visuals, headspace, body load, and auditory effects

    Visual Intensity ×3
    10
    autonomous entities drifting colour shifting brightened colour visual distortions
    Headspace Depth ×3
    10
    introspection emotion enhancement personal bias suppression time distortion confusion
    Auditory Effects ×1
    8
    ⚠ Body Load / Somatic Effects ×1
    10
    nausea muscle tension
    Dissociative 4.3
    Moderate 4/10

    Strong motor impairment and mania with moderate insight, mild dissociative depth

    Dissociative Depth ×3
    5
    spatial disorientation memory suppression
    ⚠ Mania / Compulsion ×1
    9
    restlessness stimulation euphoria
    Insight / Novel Thought ×2
    7
    analysis enhancement introspection personal bias suppression
    ⚠ Motor / Sensory Impairment ×1
    10
    ataxia spatial disorientation
    Opioid 4.7
    Moderate+ 5/10

    Strong itching/nausea and euphoria with low pain relief and sedation

    Euphoria / Warmth ×3
    9
    euphoria
    Analgesia ×2
    2
    Sedation / Relaxation ×1
    2
    ⚠ Itching / Nausea ×1
    10
    nausea
    Based on reports from:
    TiHKAL TiHKAL #25: Ibogaine Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki Ibogaine The Drug Users Bible Ibogaine
    View methodology →

    Tolerance

    Build-up not applicable — typically used as a single large dose
    Reset not applicable

    Tolerance Decay

    Full tolerance 0h Half tolerance 1d Baseline ~7d

    Acute tachyphylaxis to re-dosing is common due to persistent noribogaine; functional sensitivity returns over days–weeks. Repeated high-dose use is uncommon due to intensity and cardiotoxic window.

    Cross-Tolerances

    Classical psychedelics (5-HT2A agonists)
    30%

    Effects Erowid Bluelight

    Aggregated from 46 Erowid and 17 Bluelight experience reports

    Positive Effects 33

    Stimulation 58.7% 70%
    Anxiety Suppression 54.0% 82%
    Color Enhancement 52.2% 70%
    Empathy 42.8% 85%
    Introspection 41.3% 78%
    Music Enhancement 33.4% 81%
    Euphoria 33.3% 90%
    Focus Enhancement 31.7% 75%
    Body High 30.1% 70%
    Insight 23.5% 86%
    Mystical Quality 17.6% 83%
    Awe 17.6% 77%
    Out-Of-Body Experience 17.6% 87%
    Sedation 12.7% 75%
    Emotional Release 11.8% 82%
    Empathogenic Connection 11.8% 78%
    Geometric Imagery 11.8% 82%
    Contentment 11.8% 80%
    Mood Elevation 11.8% 85%
    Creativity Enhancement 10.9% 70%

    Adverse Effects 37

    Body Load 52.9% 84%
    Nausea 50.8% 85%
    Fear 47.1% 84%
    Dizziness 35.3% 85%
    Confusion 35.0% 80%
    Motor Impairment 33.3% 79%
    Insomnia 29.4% 86%
    Increased Heart Rate 19.6% 70%
    Visual Trails 17.6% 83%
    Heaviness 17.6% 78%
    Depersonalization 17.6% 72%
    Vomiting 17.6% 88%
    Restlessness 17.6% 80%
    Vertigo 11.8% 88%
    Thought Loops 11.8% 72%
    Depression 11.8% 82%
    Emotional Blunting 11.8% 78%
    Ataxia 11.8% 85%
    Pain Enhancement 11.8% 80%
    Visual Vibration 11.8% 85%

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    TiHKAL #25: Ibogaine
    Ibogaine's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

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