Isomethadone Stats & Data
NPS DataHub
MW309.45
FormulaC21H27NO
CAS466-40-0
IUPAC6-(dimethylamino)-5-methyl-4,4-diphenylhexan-3-one
SMILES
CCC(=O)C(C(C)CN(C)C)(c1ccccc1)c1ccccc1InChIKey
IFKPLJWIEQBPGG-UHFFFAOYSA-N
Chemical Class
Opioid
Psychoactive Class
Depressant
History & Culture
Isomethadone, also known by the alternative name isoamidone, is a synthetic opioid analgesic structurally related to methadone. It was previously marketed as a pharmaceutical product under the trade name Liden, where it saw clinical use for both pain management and cough suppression. The compound has since been withdrawn from the pharmaceutical market and is no longer commercially available as a medication.
Effect Profile
Curated
Opioid
5.4
Moderate euphoria with mild pain relief and itching/nausea, low sedation
Euphoria / Warmth×3
7
Analgesia×2
4
Sedation / Relaxation×1
3
Itching / Nausea×1
4
Based on reports from:
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~35d