Isophenmetrazine
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- classified Tentative
- classified Research-chemical
- 2 corroborating sources
- 2 ROAs with full dose ladders
- duration data present
- classified Tentative
- classified Research-chemical
Summary
Rare and little known analogue of phenmetrazine, which is slightly more potent than other analogues. Probably a stimulating, appetite supressing drug with high addiction potential. Potentially a dopamine and/or norepinephrine releasing agent.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 2-5mg | 5-15mg | 20-40mg | 40mg+ |
| Oral | 5-10mg | 10-20mg | 20-50mg | 50mg+ |
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Oral | 15-30 min | 3-5 hrs |
Effect Profile
class estimateScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- No reports exist for this substance. Its effect list is the one shared by 3 other substances of the same class, so the scores below describe the class, not this compound.
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong anxiety/jitters with moderate stimulation and euphoria
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Isophenmetrazine there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Isophenmetrazine Source: SubstanceSearch (substancesearch.com) Insufflated dose (mg): light 2-5 · common 5-15 · strong 20-40 · heavy 40+ Oral dose (mg): light 5-10 · common 10-20 · strong 20-50 · heavy 50+ Insufflated duration: after-effects 1-6h Oral duration: onset 15-30m · peak 3-5h · after-effects 1-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 10 mg (Insufflated).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Mental/physical stimulation
- Increased heart rate
- Insomnia
- Pupil dilation
- Nausea
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
- Alertness enhancement
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
- Anxiety
- Confusion
- Compulsive redosing
- Talkativeness
- Time distortion
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
- Light sensitivity
- Disinhibition
- Appetite suppression
- Dehydration
- Dulled perception
- Drifting
Helpful Links
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