mCPP Stats & Data
Cpp
3-cpp
Meta-chlorophenylpiperazine
NPS DataHub
MW196.68
FormulaC10H13ClN2
CAS6640-24-0
IUPAC1-(3-Chlorophenyl) piperazine
SMILES
Clc1cccc(c1)N1CCNCC1InChIKey
VHFVKMTVMIZMIK-UHFFFAOYSA-N
Psychoactive Class
Stimulant
Pharmacology
DrugBankDescription
m-Chlorophenylpiperazine has been used in trials studying the treatment of Alcoholism.
Receptor Profile
Receptor Actions
Agonists
5-HT2B receptor partial agonist
5-HT2C receptor partial agonist
Antagonists
5-HT2A receptor antagonist
Inhibitors
Serotonin reuptake inhibitor
Other
Serotonin releasing agent
Receptor Binding
serotonin
reuptake inhibitor
It is strongly recommended that one use harm reduction practices when using this drug.
Carcinogenicity
2B, possibly carcinogenic to humans. (L135)
Effect Profile
Curated + 7 Reports
Stimulant
4.1
Strong anxiety/jitters with moderate stimulation, mild euphoria
Stimulation / Energy×3
7
Euphoria / Mood Lift×2
5
Focus / Productivity×2
0
Anxiety / Jitters×1
8
Based on reports from:
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
1d
Half tolerance
10d
Baseline
~18d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Experience Report Analysis
Erowid
7
Reports
2005–2009
Date Range
1
With Age Data
10
Effects Detected
Demographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 7 experience reports (7 Erowid)
7
Reports
10
Effects Detected
4
Positive
5
Adverse
1
Neutral
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 4
Euphoria
100.0%
70%
Color Enhancement
57.1%
70%
Tactile Enhancement
57.1%
70%
Stimulation
42.9%
70%
Adverse Effects 5
Anxiety
85.7%
70%
Nausea
85.7%
70%
Jaw Clenching
57.1%
70%
Pupil Dilation
57.1%
70%
Headache
42.9%
70%
Real-World Dose Distribution
62K DosesFrom 1 individual dose entries
Form / Preparation
Most common forms and preparations reported
Legal Status
| Country | Status | Notes |
|---|---|---|
| Austria | Since January 1, 2012, mCPP is illegal to possess, produce and sell under the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich). | |
| Belgium | mCPP is a controlled substance as of October 22, 2006. | |
| Brazil | mCPP is a controlled substance ( lista F2 da Portaria SVS/MS 344/98 ) since November 2008. | |
| China | As of October 2015, mCPP is a controlled substance in China. | |
| Denmark | mCPP is a controlled substance as of December 3, 2005. | |
| Finland | mCPP is a controlled substance. | |
| Germany | mCPP is controlled under Anlage II BtMG ( Narcotics Act, Schedule II ) as of March 1, 2007. | It is illegal to manufacture, possess, import, export, buy, sell, procure or dispense it without a license. |
| Greece | mCPP is a controlled substance as of January 20, 2005. | |
| Hungary | mCPP is a controlled substance as of January 1, 2006. | |
| Japan | mCPP is a controlled substance since 2006. | |
| Lithuania | mCPP is a controlled substance as of July 1, 2006. | |
| Norway | mCPP is a controlled substance. | |
| Poland | mCPP is a controlled substance. | |
| Russia | mCPP is a controlled substance. | |
| Sweden | mCPP is a controlled substance. | |
| Switzerland | mCPP is a controlled substance specifically named under Verzeichnis D. | |
| United Kingdom | mCPP is a Class C, Schedule 4 (Part 1) drug in the United Kingdom. | |
| United States | mCPP is unscheduled in the United States, but could be considered an analogue of benzylpiperazine if it is sold for human consumption. |
References
Cited References
- Bossong et al. 2010: mCPP Ecstasy Market Study
- Erowid: mCPP Experience Vault
- Gijsman et al. 2002: Pharmacokinetic Profile of mCPP
- Kennett et al. 1989: Anxiogenic Effects of mCPP
- Leone et al. 2000: mCPP-Induced Migraine Study
- NCATS Inxight Drugs: mCPP Monograph
- PDSP Ki Database: mCPP Receptor Binding
- Release UK: mCPP Pharmacology
- Rotzinger et al. 1998: CYP2D6 Metabolism of mCPP
- Wikipedia: meta-Chlorophenylpiperazine