Summary
MD-prolintane is the 3,4-methylenedioxy analogue of prolintane and structurally the de-ketone counterpart of MDPV. Users describe functional, cocaine-like stimulation with reduced peripheral tension compared to alpha-PVP. Duration is approximately 4-6 hours with reports of smoother comedowns than related pyrrolidinophenones. High oral bioavailability is reported; insufflation increases potency but causes nasal irritation. Use accurate scales for dosing as the compound is dense.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 1-3 hrs | 1-2 hrs | 2-12 hrs |
| Insufflated | 5-10 min | 10-20 min | 1-3 hrs | 1-2 hrs | 2-12 hrs |
| Vaporized / Smoked | 2 min | 5-10 min | 1-3 hrs | 1-2 hrs | 2-12 hrs |
| Intravenous | 1 min | 1-5 min | 1-3 hrs | 1-2 hrs | 2-12 hrs |
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute; 1–3 weeks for full reset
Effects
Positive
- Stimulation
- Physical euphoria
Negative
- Increased heart rate
- Teeth grinding
- Vasoconstriction
- Increased perspiration
- Increased blood pressure
- Insomnia
- Sweating
- Temperature regulation suppression
Positive
- Focus enhancement
- Motivation enhancement
- Cognitive euphoria
- Wakefulness
- Euphoria
Negative
- Anxiety
- Compulsive redosing
- Paranoia
- Thought acceleration
- Time distortion
Positive
- Increased libido
- Increased music appreciation
- Tactile enhancement
Negative
- Appetite suppression
- Light sensitivity
- Dehydration
- Disinhibition
- Appetite Suppression
- Vibrating vision
- Increase sexuality