MD-prolintane
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 1 source
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
- 1 source
- duration data present
- 18 combo interactions documented
- classified Research-chemical
- dose data not in PW/TripSit (unverifiable)
Aliases: Methylenedioxyprolintane
Summary
MD-prolintane is the 3,4-methylenedioxy analogue of prolintane and structurally the de-ketone counterpart of MDPV. Users describe functional, cocaine-like stimulation with reduced peripheral tension compared to alpha-PVP. Duration is approximately 4-6 hours with reports of smoother comedowns than related pyrrolidinophenones.
Dose Information
| ROA | Threshold |
|---|---|
| Oral | 2mg |
| Insufflated | 2mg |
| Vaporized / Smoked | 2mg |
| Intravenous | 1mg |
Only a threshold dose is documented for this substance โ the smallest amount with a noticeable effect. There is no published light/common/strong ladder to show above it.
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 20-40 min | 30-60 min | 1-3 hrs | 1-2 hrs | 2.83-6.67 hrs |
| Insufflated | 5-10 min | 10-20 min | 1-3 hrs | 1-2 hrs | 2.25-5.5 hrs |
| Vaporized / Smoked | 2 min | 5-10 min | 1-3 hrs | 1-2 hrs | 2.11-5.2 hrs |
| Intravenous | 1 min | 1-5 min | 1-3 hrs | 1-2 hrs | 2.04-5.1 hrs |
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong euphoria and anxiety/jitters with moderate focus, mild stimulation
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MD-prolintane Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 2 Insufflated dose (mg): threshold 2 Vaporized / Smoked dose (mg): threshold 2 Intravenous dose (mg): threshold 1 Oral duration: onset 20-40m ยท come-up 0.5-1h ยท peak 1-3h ยท offset 1-2h ยท total 2.83-6.67h ยท after-effects 2-12h Insufflated duration: onset 5-10m ยท come-up 10-20m ยท peak 1-3h ยท offset 1-2h ยท total 2.25-5.5h ยท after-effects 2-12h Vaporized / Smoked duration: onset 2m ยท come-up 5-10m ยท peak 1-3h ยท offset 1-2h ยท total 2.11-5.2h ยท after-effects 2-12h Intravenous duration: onset 1m ยท come-up 1-5m ยท peak 1-3h ยท offset 1-2h ยท total 2.04-5.1h ยท after-effects 2-12h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session โ the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Physical euphoria
- Increased heart rate
- Teeth grinding
- Vasoconstriction
- Increased perspiration
- Increased blood pressure
- Insomnia
- Sweating
- Temperature regulation suppression
- Focus enhancement
- Motivation enhancement
- Cognitive euphoria
- Wakefulness
- Euphoria
- Anxiety
- Compulsive redosing
- Paranoia
- Thought acceleration
- Time distortion
- Increased libido
- Increased music appreciation
- Tactile enhancement
- Appetite suppression
- Light sensitivity
- Dehydration
- Disinhibition
- Vibrating vision
- Increase sexuality
Combinations
Cross-Check MD-prolintane with another substanceHelpful Links
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