MDEA Stats & Data
[Cl-].CCNC(C)Cc1ccc2OCOc2c1.[H+]IBDIPBWIXJRJQM-UHFFFAOYSA-NPharmacology
DrugBankDescription
3,4-Methylenedioxyamphetamine (also known as MDA, and Tenamfetamine, or colloquially as "Sally", "Sass", or "Sass-a-frass") is a synthetic entactogen of the amphetamine chemical class. It produces long-lived entactogenic, stimulant and mild psychedelic effects that include stimulation, anxiety suppression, enhanced feelings of empathy, affection, and sociability, and euphoria when administered. MDA was first synthesized in 1910 but its psychoactive effects were not discovered until in 1930. It was used in animal and human trials between 1939 and 1941 and from 1949 to 1957. More than 500 human subjects were given MDA in an investigation of its potential use as either an antidepressant or anorectic. By 1958, it was successfully patented as a cough suppressant and ataractic. By 1961 it was patented as an anorectic under the trade name "Amphedoxamine".citation needed Contemporary reports suggest that MDA emerged as a recreational drug towards the end of 1967, meaning its use predates its more widely used relative MDMA (Ecstasy). As with MDMA, MDA is thought to act primarily as a serotonin-norepinephrine-dopamine reuptake inhibitor and releasing agent.citation needed However, MDA is significantly more potent by weight and subjective intensity relative to MDMA.
Receptor Profile
Receptor Actions
Effect Profile
Curated + 9 ReportsModerate body load with low headspace
Strong euphoria and sensory enhancement with moderate stimulation, low empathy
Strong euphoria and anxiety/jitters with mild stimulation, low focus
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 9 experience reports (9 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 8
Adverse Effects 8
Real-World Dose Distribution
62K DosesFrom 12 individual dose entries
Oral (n=7)
Form / Preparation
Most common forms and preparations reported
Legal Status
| Country | Status | Notes |
|---|---|---|
| Austria | MDEA is illegal to possess, produce and sell under the SMG (Suchtmittelgesetz Österreich). | |
| Brazil | MDEA is illegal to possess, produce or sell as it is listed on Portaria SVS/MS nº 344 as "MDE". | |
| Canada | MDEA is listed on the CSDA in Schedule I. | |
| France | MDEA is scheduled as a "stupéfiant", i.e. | a recognized drug of abuse. It is illegal to possess, buy, sell or manufacture. |
| Germany | MDEA is controlled under Anlage I BtMG (Narcotics Act, Schedule I) as of April 15, 1991. | It is illegal to manufacture, possess, import, export, buy, sell, procure or to dispense it without a license. ( MDE ) |
| Switzerland | MDEA is a controlled substance specifically named under Verzeichnis D. | |
| United Kingdom | MDEA is a Class A drug. | |
| United States | In the United States, MDEA was introduced recreationally in 1985 as a legal substitute to the newly banned MDMA. | MDEA was made a Schedule 1 substance in the United States on October 15, 1987. |