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    πŸ§ͺ This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    MDEA is a Schedule I controlled substance in most countries. The substance is characterized by a more sedating, 'stoning' quality compared to MDMA, with less emphasis on social connection and more on physical relaxation. MDEA requires careful dosing with an accurate milligram scale, adequate hydration without over-drinking, and temperature regulation in warm environments.

    Perspectives

    “There was a warm light all about me. And a gentle, almost alcohol-like, intoxication. The drug seems to change my state of awareness, but it does nothing else. The world is as intense or as dull as I choose to make it. At the 1.5 hour point I was clearly dropping, and an hour later yet, completely without residue.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 70-120mg 120-180mg 180-225mg 225mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 18-60 min 12-30 min 1.5-2 hrs 1-2 hrs 12-48 hrs 3-5.5 hrs

    Effect Profile

    9 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 0.8
    Threshold 1/10

    Moderate body load with low headspace

    Visual Intensity ×3
    0
    Headspace Depth ×3
    1
    time distortion
    Auditory Effects ×1
    0
    Body Load / Somatic Effects ×1
    7
    temperature regulation suppression teeth grinding increased heart rate
    Empathogen 6.1
    Strong 6/10

    Strong euphoria and sensory enhancement with moderate stimulation, low empathy

    Empathy / Social Openness ×3
    3
    empathy, affection, and sociability enhancement
    Euphoria / Mood Elevation ×2
    10
    physical euphoria cognitive euphoria
    Stimulation ×1
    6
    stimulation teeth grinding increased heart rate
    Sensory Enhancement ×1
    8
    tactile enhancement increased libido
    Stimulant 4.8
    Moderate+ 5/10

    Strong euphoria and anxiety/jitters with mild stimulation, low focus

    Stimulation / Energy ×3
    4
    stimulation alertness enhancement
    Euphoria / Mood Lift ×2
    10
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    3
    motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute; 1–3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 12d Baseline ~21d

    Effects Erowid

    Aggregated from 9 Erowid experience reports

    Positive Effects 8

    Focus Enhancement 66.7% 70%
    Stimulation 66.7% 70%
    Color Enhancement 55.6% 70%
    Empathy 55.6% 70%
    Euphoria 55.6% 70%
    Tactile Enhancement 55.6% 70%
    Body High 33.3% 70%
    Introspection 33.3% 70%

    Adverse Effects 8

    Confusion 55.6% 70%
    Jaw Clenching 55.6% 70%
    Increased Heart Rate 44.4% 70%
    Anxiety 44.4% 70%
    Sweating 44.4% 70%
    Nausea 44.4% 70%
    Headache 33.3% 70%
    Muscle Tension 33.3% 70%

    Combinations TripSit

    PiHKAL / TiHKAL Shulgin

    PiHKAL #106: MDE

    “There was a warm light all about me. And a gentle, almost alcohol-like, intoxication. The drug seems to change my state of awareness, but it does nothing else. The world is as intense or as dull as I choose to make it. At the 1.5 hour point I was clearly dropping, and an hour later yet, completely without residue.”

    β€” Alexander Shulgin, PiHKAL (with 100 mg)

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