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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    MDEA Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 5 corroborating sources
    • 1 ROA with full dose ladder
    • duration data present
    • 20 combo interactions documented
    • PubChem toxicity data
    • classified Tentative
    • classified Research-chemical

    Aliases: Mde, Eve

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    MDEA is a Schedule I controlled substance in most countries. The substance is characterized by a more sedating, 'stoning' quality compared to MDMA, with less emphasis on social connection and more on physical relaxation. MDEA requires careful dosing with an accurate milligram scale, adequate hydration without over-drinking, and temperature regulation in warm environments.

    Perspectives

    “There was a warm light all about me. And a gentle, almost alcohol-like, intoxication. The drug seems to change my state of awareness, but it does nothing else. The world is as intense or as dull as I choose to make it. At the 1.5 hour point I was clearly dropping, and an hour later yet, completely without residue.”

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 70-120mg 120-180mg 180-225mg 225mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 18-60 min 12-30 min 1.5-2 hrs 1-2 hrs 12-48 hrs 3-6 hrs

    Effect Profile

    9 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Psychedelic 0.8
    Threshold 1/10

    Moderate body load with low headspace

    Visual Intensity ×3
    0
    Headspace Depth ×3
    1
    time distortion
    Auditory Effects ×1
    0
    Body Load / Somatic Effects ×1
    7
    temperature regulation suppression teeth grinding increased heart rate
    Empathogen 6.1
    Strong 6/10

    Strong euphoria and sensory enhancement with moderate stimulation, low empathy

    Empathy / Social Openness ×3
    3
    empathy, affection, and sociability enhancement
    Euphoria / Mood Elevation ×2
    10
    physical euphoria cognitive euphoria
    Stimulation ×1
    6
    stimulation teeth grinding increased heart rate
    Sensory Enhancement ×1
    8
    tactile enhancement increased libido
    Stimulant 4.8
    Moderate+ 5/10

    Strong euphoria and anxiety/jitters with mild stimulation, low focus

    Stimulation / Energy ×3
    4
    stimulation alertness enhancement
    Euphoria / Mood Lift ×2
    10
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    3
    motivation enhancement thought acceleration
    Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3โ€“7 days for acute; 1โ€“3 weeks for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 36d Baseline ~90d

    Effects Erowid

    Aggregated from 9 Erowid experience reports

    Positive Effects 8

    Focus Enhancement 66.7% 70%
    Stimulation 66.7% 70%
    Color Enhancement 55.6% 70%
    Empathy 55.6% 70%
    Euphoria 55.6% 70%
    Tactile Enhancement 55.6% 70%
    Body High 33.3% 70%
    Introspection 33.3% 70%

    Adverse Effects 8

    Confusion 55.6% 70%
    Jaw Clenching 55.6% 70%
    Increased Heart Rate 44.4% 70%
    Anxiety 44.4% 70%
    Sweating 44.4% 70%
    Nausea 44.4% 70%
    Headache 33.3% 70%
    Muscle Tension 33.3% 70%

    Combinations TripSit

    Cross-Check MDEA with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 4 reports 4 neutral visit
    Unique - Similar to, but Not Like MDMA neutral exp #89967

    Background: I first took mdma 9 years ago. I have strong experience with mdma, mda, lsd, mushrooms, mescaline (teas and the extracted hcl salt). I have extensive experience with numerous other drugs/psychedelics but that's not important to know for reading this experience so Iย’ll leave it at that for now.

    The Fresh Prince · 150 mg oral / 0.5 mg oral
    Connecting on New Years 99-00 neutral exp #2017

    Material : The MDE was from a reliable source in the form of hard powder chunks in capsules. The certainty of material was pretty high. The MDE powder tastes bitter, especially strong on the front of the tongue. Zam thinks it tastes about the same as MDMA, while Zara thinks it's not quite as bitter as MDMA or 2CB.

    Zam · MDE · 150 mg oral
    Window To My Own Fears neutral exp #19141

    I was traveling across the country with a friend and came upon an old buddy of his who had purchased a jar of 'MDE'. I had never experienced this before and was curious to find out what, if any differance there might be from MDMA. After ingestion, the pill kicked in surprisingly fast, aprox. 15 minutes...FULL SWING.

    Cramer · MDE
    Clear and Centered neutral exp #2018

    Okay, so we took some of what we were told was MDE, to mark the new year. We are mostly sure that it was in fact MDE, but it's difficult to be sure. 12:27 am (T+ 0) - We threw down. The tablets were diamond-shaped, fairly small, with brown specks.

    Bug · MDE · 1 tablet oral
    Bluelight 6 threads 6 neutral visit
    Mdea 50 Mg 100 Mg First Time The Guinea Pig Friend neutral

    i thought i'd share this here since MDEA trip reports are so rare to find online. the MDEA was pure, not a pressed pill. so enclosed are 2 trip reports. the first is a trip report by my friend. then under the "======" break is my trip report.

    scraped 2026-03-14
    Rolling For The First Time At Life 2004 05 New Years Eve neutral

    Rolling for the first time at LIFE 2004/05, New Years Eve Dose: 1/6th gram of lovely MDMA 1 white Mitsubishi 1 double cherry This was my first proper experience on ecstasy, been meaning to right this up for quite a while so lets see how the memory holds! My two friends and I went to Milton Keynes for our first rave, th...

    scraped 2026-03-14
    New Years Eve Report neutral

    This happend a couple of months ago on new years day in 2012 (leading onto 2013), I was 17 at the time and im 6ft and quite broad and built.. if that makes any difference...

    scraped 2026-03-14
    Mdea First Time Definitely A Fun Drug neutral

    my first MDEA experiance, i was sold crystals which were openly sold as MDEA not MDMA or MDA, they were rather cheap $50 canadian, for a gram so i bought a gram and split it with 2 friends the experiance is as follows: T0:00-weight out 200mgs each and wash it down with some water T0:30-starting to feel pretty floored h...

    scraped 2026-03-14
    Mde 350mg Inexperienced Complete Bliss neutral

    MDEA(MDE) - 350mg experienced Most people i have come across on these forums seem to beleive MDE is nothing more then some sort of inerior cousin to MDMA. I have personally found this drug to be just as enjoyable experience as MDMA, although it is more of a "stoned" type high as opposed to a light as feathers dancy ecs...

    scraped 2026-03-14
    Christmas Eve Shroomfest neutral

    well just a few days back I got a quarter of some gold cap p. cubenis mushrooms from my dealer as an Xmas gift while I picked up this half oz of blue dream bud. it was Christmas Eve.

    scraped 2026-03-14

    PiHKAL / TiHKAL Shulgin

    PiHKAL #106: MDE

    “There was a warm light all about me. And a gentle, almost alcohol-like, intoxication. The drug seems to change my state of awareness, but it does nothing else. The world is as intense or as dull as I choose to make it. At the 1.5 hour point I was clearly dropping, and an hour later yet, completely without residue.”

    โ€” Alexander Shulgin, PiHKAL (with 100 mg)

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