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    Mephenaqualone Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 1 source
    • 1 ROA with full dose ladder
    • duration data present
    • toxicity data (PsychonautWiki)

    Depressant

    Summary PsychonautWiki

    Mephenaqualone is a central nervous system (CNS) depressant of the quinazolinone class that acts as a sedative and hypnotic. It is an analogue of methaqualone, sharing a similar chemical structure and pharmacological effects.

    Dose Information PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 0.5-1.5mg 1.5-2.5mg 2.5-4mg 4mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-42 min 6-12 min 2-4 hrs 10-15 hrs 6-12 hrs 12.6-19.9 hrs

    Import into PsychonautWiki Journal

    The PsychonautWiki Journal app includes Mephenaqualone, but its built-in data can be thinner than ours. Importing this file adds a separate "Mephenaqualone (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.

    ⬇ Download import file Import this file as custom substances and you get "Mephenaqualone (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer.

    Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up develops over 1–4 weeks of regular use
    Reset days to weeks depending on duration of use

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects

    Positive
    • Muscle relaxation
    • Physical euphoria
    • Anxiolytic
    • Muscle Relaxant
    Negative
    • Motor impairment
    • Respiratory depression
    Neutral
    • Sedation
    • Sedative
    • Dystaxia
    • Hypnotic
    Positive
    • Reduced anxiety
    • Anxiety suppression
    • Dream potentiation
    • Cognitive euphoria
    Negative
    • Motor control loss
    • Amnesia
    • Thought deceleration
    • Dizziness
    • Compulsive redosing
    • Constipation
    Positive
    • Increased libido
    • Tactile enhancement
    Negative
    • Disinhibition
    • Acuity suppression
    • Double vision
    Neutral
    • Dulled perception
    • Visual disconnection
    • Internal hallucination
    • Changes in gravity
    • Internal hallucinations
    Mephenaqualone's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 PsychonautWiki