Home
    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    Methiopropamine

    Aliases: Mpa, Blow

    Stimulant Research-chemical

    Summary TheDrug.Wiki Erowid TripSit PsychonautWiki

    Methiopropamine (also known as MPA) is a stimulant substance of the thiophene class. It is a ring-based structural analogue of methamphetamine. Methiopropamine was first synthesized in 1942.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 20-30mg 30-50mg 50-60mg 60mg+
    Insufflated 5-20mg 20-40mg 40-60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-60 min 30-60 min 2-4 hrs 2-3 hrs 1-2 hrs 5-9 hrs
    Insufflated 5-10 min 10-20 min 30-60 min 0.5-2 hrs 6-8 hrs 1.2-3.5 hrs

    Effect Profile

    28 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Validated against 28 Erowid trip reports
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Stimulant 8.8
    Intense+ 9/10

    Strong stimulation, euphoria, focus, and anxiety/jitters

    Stimulation / Energy ×3
    10
    stimulation wakefulness
    Euphoria / Mood Lift ×2
    10
    physical euphoria cognitive euphoria motivation enhancement
    Focus / Productivity ×2
    10
    focus enhancement analysis enhancement motivation enhancement thought acceleration
    ⚠ Anxiety / Jitters ×1
    10
    anxiety teeth grinding increased heart rate
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Methiopropamine
    View methodology →

    Tolerance

    Build-up develops over days to weeks of regular use
    Reset 3–7 days for acute tolerance; longer for full reset

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Effects Erowid

    Aggregated from 28 Erowid experience reports

    Positive Effects 9

    Stimulation 71.4% 70%
    Euphoria 64.3% 70%
    Focus Enhancement 53.6% 70%
    Empathy 42.9% 70%
    Music Enhancement 35.7% 70%
    Tactile Enhancement 25.0% 70%
    Body High 21.4% 70%
    Color Enhancement 14.3% 70%
    Creativity Enhancement 10.7% 70%

    Adverse Effects 9

    Anxiety 42.9% 70%
    Jaw Clenching 25.0% 70%
    Pupil Dilation 25.0% 70%
    Increased Heart Rate 25.0% 70%
    Confusion 21.4% 70%
    Nausea 17.9% 70%
    Headache 17.9% 70%
    Sweating 14.3% 70%
    Appetite Suppression 10.7% 70%
    Methiopropamine's nerd page Pharmacology, chemical data, effect profiles, and more
    →

    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 PsychonautWiki