Methiopropamine Well-documented

Well-documented

Multiple authoritative sources agree on dosing and effects.

6 corroborating sources

2 ROAs with full dose ladders

duration data present

toxicity data (PsychonautWiki)

classified Research-chemical

Aliases: Mpa, Blow

Summary dose.wiki Erowid TripSit PsychonautWiki

Methiopropamine (also known as MPA) is a stimulant substance of the thiophene class. It is a ring-based structural analogue of methamphetamine. Methiopropamine was first synthesized in 1942.

Dose Information PsychonautWiki

ROA	Light	Common	Strong	Heavy
Oral	20-30mg	30-50mg	50-60mg	60mg+
Insufflated	5-20mg	20-40mg	40-60mg	60mg+

Light Common Strong Heavy

Sources

Oral

Dose ladder — dose.wiki, PsychonautWiki

Insufflated

Dose ladder — PsychonautWiki

Onset, Duration & After-effects dose.wiki TripSit PsychonautWiki

ROA	Onset	Comeup	Peak	Offset	After Effects	Total
Oral	30-60 min	30-60 min	2-4 hrs	2-3 hrs	1-2 hrs	6-10 hrs
Insufflated	5-10 min	10-20 min	30-60 min	0.5-2 hrs	6-8 hrs	2-4 hrs

Effect Profile

17 reports

Scores (0–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Stimulant 6.1

Strong 6/10

Strong focus with strong anxiety/jitters, moderate euphoria, mild stimulation

Stimulation / Energy ×3

stimulation wakefulness

Euphoria / Mood Lift ×2

physical euphoria cognitive euphoria motivation enhancement

Focus / Productivity ×2

focus enhancement analysis enhancement motivation enhancement thought acceleration

⚠ Anxiety / Jitters ×1

anxiety teeth grinding increased heart rate

Based on reports from:

Erowid Experience Reports PsychonautWiki Methiopropamine

Tolerance

Build-up develops over days to weeks of regular use

Reset 3–7 days for acute tolerance; longer for full reset

Tolerance Decay

Full tolerance 1d Half tolerance 10d Baseline ~18d

Effects Erowid

Aggregated from 17 single-substance Erowid experience reports; 11 Erowid reports where another drug was taken too are left out

Each bar shows the share of analyzed reports whose text mentions that effect — a mention is not always a first-hand experience (fear of an effect or something witnessed can count). Mentions saying the effect did not happen are left out; that check reads keywords, so it can miss some. The shaded band on a bar, and the small range after its number, is the 95% interval: where the share could plausibly be with other reports of the same kind. Fewer reports, wider band. Tap or hover any number for details. The second value is the Bluelight extractor's per-effect confidence; a dash means the row is Erowid-derived, which has no confidence measurement.

Too few reports for bars: these effects come from 17 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

Positive Effects 7

11 of 17 –

8 of 17 –

6 of 17 –

5 of 17 –

3 of 17 –

Adverse Effects 4

6 of 17 –

4 of 17 –

3 of 17 –

Also reported in combinations. In the 11 Methiopropamine reports where another drug was taken too, 0 mention hospital, emergency services or an overdose, 0 a seizure and 1 psychosis (too few reports for percentages). In the 17 single-substance reports: 1, 0 and 0. These are not in the figures above: they cannot be put down to Methiopropamine alone, and a mention is not always something that happened to the writer.

Community Trip Reports

Anecdotal first-person accounts from Reddit, Erowid, Bluelight, and Dose.wiki. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.

Erowid 8 reports 3 positive 4 neutral 1 cautionary visit

A Very Sober Stimulant positive exp #93121

This is a report of two different occasions using MPA, or Methiopropamine; the first can be seen as background and context for using the drug together with the first account of my initial experience snorting the drug.

Interesting to Say the Least positive exp #110473

Substance Background: For clarification my substance 'use' over the past two years has been inexistent. However, the substances I will list here are things I used years ago.

Pleasant but Nothing Great neutral exp #101371

The backstory: After meeting with some friends that had taken methiopropamine in the form of a legal high mixed with benzocaine (Ethyl 4-aminobenzoate), presumably to combat the quite painful snorting, in an unspecified ratio, my friend and I decided wed try it after a bit of research.

More More More--Yet a Relaxing Stimulant neutral exp #103207

Some user details have been slightly modified for privacy, but all of the following information is completely true and carefully recorded. Background on me: mildly bipolar, longtime chronic mild anxiety sufferer, access to benzos both rc and prescribed.

Attentitive, Focused, Willing to Work cautionary exp #94912

I've been researching chems to ingest for the purpose of study over the last year. I've tried a few of the racetams, (pir, ani and oxi) finding that oxi gave me near photographic memory while piracetam seems completely inactive.

Relief at Last neutral exp #92416

I have experienced narcoleptic symptoms for roughly a dozen years; and no treatment, mainstream or otherwise, has exhibited fewer side-effects than methiopropamine (i.e. MPA).

Research Chemical Amphetamine Replacement neutral exp #96119

(decided to start documenting at 3:45PM, times up until then are estimates.) Today I awoke at about 1:30 from a night of watching the first 4 episodes of Breaking Bad. Through the night I remember having very weird dreams that seemed extremely inspired by Breaking Bad.

What Once Excited... Does Not positive exp #102434

I am a 28 year old artist with a fairly logical and normal state of mind. I wouldn't consider myself to be paranoid and/or over the top. I am currently on no medication but have suffered from depression in the past.

Bluelight 7 threads 3 positive 3 neutral 1 cautionary visit

Mpa 100mg Experienced Mpa Notes And Periodic Vital Check Throughout The Day positive

I have taken MPA in the past with mixed results. It has always been either very good (productive, worthwhile, no problems) or had started out OK but quickly began making me feel very sick. Anyway, I'm tired of Monster and coffee which aren't doing much because I haven't slept since I got up on Friday at 4:00 PM.

Methiopropamine Multiple Doses Experienced Satisfying And Loveable positive

Background : I've been prescribed Adderall (30mg/twice daily) for about a year now, the first 6 months of having it I abused it a lot, snorting it and taking way too many at one time.

Mpa First Few Times Research Binge neutral

As many of you will be aware, Methiopropamine was temp banned in the UK on the 27th of November. This was the day that the 1 gram I had ordered arrived in my mail. It is now two weeks later.

Methiopropamine First Time Mini Report On Treshold Dose 10mg neutral

Substance : Methiopropamine HCL Appareance : Fine white powder - clumpy and sticky First time experience on a "pure stimulant" (not empathogen) I don't have any stimulant tolerance and I have never tried a pure functional stimulant. Only experienced MDMA as "stimulant" and Methylone.

Methiopropamine Mpa Intravenous Injected Iv positive

After looking all around, I found one post on this being possible. But there was limited information on dose, effect, duration and general effects. I'm sure there as many who would like a small trip report for this ROA, with an otherwise disappointing RC.

Methiopropamine First Time Clear Headed Stimulation neutral

I bought 500mgs of this stuff off've a reputable vendor. I consumed about 200-250mg's of it over the night and gave out the rest. Not sure exact doses though. It was a clumpy white powder and every dose was snorted.

Methiopropamine 20 25 Mg First Time Not A Nice Trip cautionary

Hi I am new to Blulight , I used to post on champlegals before it was closed but I stopped once cathinones were controlled as there was nothing new to report. I am healthy and was in a good frame of mind at the time of taking this substance. I recieved a sample or Methiopropamine from a reputable supplier.

Methiopropamine's nerd page Pharmacology, chemical data, effect profiles, and more

→

Helpful Links

📘 Experience Reports 📖 dose.wiki 📖 PsychonautWiki

Add missing routes to PsychonautWiki Journal

The PsychonautWiki Journal app already has Methiopropamine, but its built-in entry only covers Insufflated, Oral. Here are the other routes we have data for. You can't edit a built-in substance, but you can add a Custom Unit for any of these routes to log it.

⬇ Download import file Import this file as custom substances and you get "Methiopropamine (Substance Search)" with every route's full dose ladder and timeline, no typing. Works on iOS and Android (v15+); the format is confirmed by the app's developer. The manual values below work for older versions.

Duration (reference)

Methiopropamine: routes the PsychonautWiki Journal app is missing
Source: SubstanceSearch (substancesearch.com)


Insufflated duration: onset 5-10m · come-up 10-20m · peak 0.5-1h · offset 0.5-2h · total 2-4h · after-effects 6-8h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

Ranges are harm-reduction guidance, not a prescription.

Report an issue or suggest an edit

Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Methiopropamine? Let us know. Reports are reviewed by moderators — this is not posted publicly.

Methiopropamine Well-documented Well-documented Multiple authoritative sources agree on dosing and effects. 6 corroborating sources 2 ROAs with full dose ladders duration data present toxicity data (PsychonautWiki) classified Research-chemical