3-MeO-2'-oxo-PCPr / MXPr - 22mg + 17mg orally For a First Trial, I'm Fairly Impressed 10-24-2019 by Xorkoth 7:20pm (T+0:00) - Weighed out and ate 22mg. I meant to go for 20, but an extra 2mg came out so I went with it. I had an intense work day and feel rather aggravated about it.
Methoxpropamine
Limited data
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- dose data not in PW/TripSit (unverifiable)
- dose ladder unverifiable and undisclosed — capped
Limited data
Sparse data. Doses and effects may be unreliable or untested.
- 2 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- 18 combo interactions documented
- dose data not in PW/TripSit (unverifiable)
- dose ladder unverifiable and undisclosed — capped
Aliases: Mxpr
Summary
Methoxpropamine is a dissociative. Reported effects include physical euphoria, pain relief, analgesia, and time distortion.
Perspectives
“Overall, it is a short and at times fairly lucid and clean experience lacking in stimulation or euphoria or weight, but with a good degree of physical dissociation and vibrant and intense colorful, flashy visuals.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 20-30mg | 30-60mg | 60-100mg | 100mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Total |
|---|---|---|---|
| Oral | 3-30 min | 2-3 hrs | 4-6 hrs |
Effect Profile
10 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Dissociative
6.0
Strong
6/10
Strong dissociative depth and motor impairment with mild mania, low insight
Dissociative Depth
×3
10
depersonalization
derealization
physical disconnection
visual disconnection
spatial disorientation
perception of bodily lightness
+2 more
Mania / Compulsion
×1
4
disinhibition
stimulation
Insight / Novel Thought
×2
3
conceptual thinking
Motor / Sensory Impairment
×1
10
motor control loss
physical disconnection
tactile suppression
numbness
spatial disorientation
visual disconnection
+1 more
Based on reports from:
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Import this file as custom substances
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Name
Methoxpropamine
Unit
mg
Description
Methoxpropamine Source: SubstanceSearch (substancesearch.com) Oral dose (mg): threshold 10 · light 20-30 · common 30-60 · strong 60-100 · heavy 100+ Oral duration: onset 3-30m · peak 2-3h · total 4-6h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 45 mg (Oral).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Tolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~28d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 10 Erowid experience reports
Positive Effects 10
Stimulation
80.0%
70%
Color Enhancement
70.0%
70%
Euphoria
70.0%
70%
Empathy
60.0%
70%
Tactile Enhancement
60.0%
70%
Music Enhancement
50.0%
70%
Focus Enhancement
40.0%
70%
Body High
40.0%
70%
Creativity Enhancement
30.0%
70%
Introspection
30.0%
70%
Adverse Effects 5
Nausea
50.0%
70%
Confusion
50.0%
70%
Motor Impairment
40.0%
70%
Anxiety
30.0%
70%
Increased Heart Rate
30.0%
70%
Combinations
Cross-Check Methoxpropamine with another substanceTrip Reports
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 7 reports 2 positive 4 neutral 1 cautionary visit
Hello, Today Id like to share a recent experience I have had with 50mg of MXPr (or 3-MeO-2-Oxo-PCPr) orally and in combination with a joint of cannabis later on. Having little information available around on this compound, I had moderate expectations but ended up being quite surprised.
Age: 24 Weight: 135 lbs Dosage: 60 mg Intranasal Setting: My apartment T0:00- Dose administered, a fairly large quantity of powder which is very light and fluffy. It stings a good bit initially but this quickly fades to an aching discomfort. After about 1 minute its really not too bad at all.
Today is the second day of a 2-day binge wherein I took a grand total of 500mg. The MXPr has all been long since consumed, I am now, at 20 hours after ingestion, still in the process of coming down, and comfortably so.
How might an oak see the world? How might a ladybug? If you could consolidate the mycelial net of a mile-wide fungal colony and put it in a two-legged body, how might its perceptions differ from yours? Imagine if it had access to the knowledge, the understanding that youve gathered through your years on Earth, but vie...
Setting: At home, in my bed Tolerance: Maybe a little, but not much (I use dissos 1-2 p. month on average). Last experience was a k-hole 17 days ago. Prior disso experience: R,S-ketamine: 25x (at least) // 2-FDCK: 5x // DCK: 5x // Nitrous Oxide: 5x // DXM (low dose): 3x // 3-MeO-PCE: 2x // 3-MeO-PCP: 1x No substa...
I feel I owe a report on this novel dissociative since there is such little info. It started on a Wednesday. I first tried 30mg insufflated to see if the reports of potency were wrong. Minor dissociation starts at +20 minutes. It is very functional at this point. Hard to tell if I'm even on a substance or not.
Bluelight 4 threads 4 neutral visit
3-MeO-2'-oxo-PCPr / MXPr - 22mg + 17mg orally For a First Trial, I'm Fairly Impressed 10-24-2019 by Xorkoth 7:20pm (T+0:00) - Weighed out and ate 22mg. I meant to go for 20, but an extra 2mg came out so I went with it. I had an intense work day and feel rather aggravated about it.
Age: 24 Weight: 135 lbs Dosage: 60 mg Intranasal Setting: My apartment T0:00- Dose administered, a fairly large quantity of powder which is very light and fluffy. It stings a good bit initially but this quickly fades to an aching discomfort. After about 1 minute its really not too bad at all.
MXPr (250 mg total, oral) - First time - Airy, invigorating, superficially revelatory 14 November, 2019 I recently obtained a small sample of MXPr, a novel dissociative that I've been hearing a little bit about for a while.
Ive posted this elsewhere on bluelight, but as requested, here it is copy and pasted into the trip reports forum: So.... I'm a god damn idiot. I fucked up big time with this chem. This is not a warning so much as a tale of stupidity. A long tale. I've just finished writing it and its definitely a tl;dr.
Bluelight Reference Guide
Dissociatives The Big and Dandy 3-MeO-2-oxo-PCPr (MXPr) Thread
I just received word from what promises to be a reliable source (there are reasons to not doubt this is true) that 3-MeO-2-oxo-PCPr, that is, MXE with a PCPr base instead of a PCE base, will be released in the near future.
Read full thread on Bluelight →
Methoxpropamine's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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