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    Methoxpropamine

    Aliases: Mxpr

    Dissociative

    Summary

    Methoxpropamine is a dissociative. Reported effects include physical euphoria, pain relief, analgesia, and time distortion.

    Dose Information

    ROA Light Common Strong Heavy
    Oral 20-30mg 30-60mg 60-100mg 100mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects

    ROA Onset Peak Total
    Oral 3-30 min 2-3 hrs 4-6 hrs

    Effect Profile

    10 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 6.0
    Strong 6/10

    Strong dissociative depth and motor impairment with mild mania, low insight

    Dissociative Depth ×3
    10
    depersonalization derealization physical disconnection visual disconnection spatial disorientation perception of bodily lightness +2 more
    ⚠ Mania / Compulsion ×1
    4
    disinhibition stimulation
    Insight / Novel Thought ×2
    3
    conceptual thinking
    ⚠ Motor / Sensory Impairment ×1
    10
    motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection +1 more
    Based on reports from:
    Effect Index St. Elmo's Fire Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki Methoxpropamine
    View methodology →

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Effects Erowid

    Aggregated from 10 Erowid experience reports

    Positive Effects 10

    Stimulation 80.0% 70%
    Euphoria 70.0% 70%
    Color Enhancement 70.0% 70%
    Empathy 60.0% 70%
    Tactile Enhancement 60.0% 70%
    Music Enhancement 50.0% 70%
    Focus Enhancement 40.0% 70%
    Body High 40.0% 70%
    Introspection 30.0% 70%
    Creativity Enhancement 30.0% 70%

    Adverse Effects 5

    Nausea 50.0% 70%
    Confusion 50.0% 70%
    Motor Impairment 40.0% 70%
    Anxiety 30.0% 70%
    Increased Heart Rate 30.0% 70%

    Combinations TripSit

    Trip Reports Effect Index

    St. Elmo's Fire nervewing
    Methoxpropamine's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 Bluelight 📖 PsychonautWiki