Methoxpropamine - Substance Search

Summary

Methoxpropamine is a dissociative. Reported effects include physical euphoria, pain relief, analgesia, and time distortion.

Perspectives

“Short sweet and intense yet hollow. A dissociative shell over a great hollow nothingness—lacking the euphoric rush of other dissociatives but with vibrant and intense colorful, flashy visuals.”

— Nervewing, nervewing.blogspot.com 60 mg intranasal

Dose Information

ROA	Light	Common	Strong	Heavy
Oral	20-30mg	30-60mg	60-100mg	100mg+

Light Common Strong Heavy

Onset, Duration & After-effects

ROA	Onset	Peak	Total
Oral	3-30 min	2-3 hrs	4-6 hrs

Effect Profile

10 reports

Scores (1–10) curated from multiple sources:

Effect keyword matching from PsychonautWiki catalog
Weighted by importance: core (×3), major (×2), minor (×1)

Full methodology

Dissociative 6.0

Strong 6/10

Strong dissociative depth and motor impairment with mild mania, low insight

Dissociative Depth ×3

10

depersonalization derealization physical disconnection visual disconnection spatial disorientation perception of bodily lightness +2 more

⚠ Mania / Compulsion ×1

4

disinhibition stimulation

Insight / Novel Thought ×2

3

conceptual thinking

⚠ Motor / Sensory Impairment ×1

10

motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection +1 more

Based on reports from:

Effect Index St. Elmo's Fire Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki Methoxpropamine

Tolerance

Build-up develops with repeated use over days to weeks

Reset 2–4 weeks for noticeable reduction

Tolerance Decay

Full tolerance 1d Half tolerance 21d Baseline ~28d

Effects Erowid

Aggregated from 10 Erowid experience reports

Positive Effects 10

Stimulation 80.0% 70%

Euphoria 70.0% 70%

Color Enhancement 70.0% 70%

Empathy 60.0% 70%

Tactile Enhancement 60.0% 70%

Music Enhancement 50.0% 70%

Focus Enhancement 40.0% 70%

Body High 40.0% 70%

Introspection 30.0% 70%

Creativity Enhancement 30.0% 70%

Adverse Effects 5

Nausea 50.0% 70%

Confusion 50.0% 70%

Motor Impairment 40.0% 70%

Anxiety 30.0% 70%

Increased Heart Rate 30.0% 70%

Combinations TripSit

Cross-Check Methoxpropamine with another substance

Trip Reports Effect Index

St. Elmo's Fire nervewing

Community Trip Reports

Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

Erowid 7 reports 7 neutral visit

For a First Trial, I'm Fairly Impressed neutral exp #113723

3-MeO-2'-oxo-PCPr / MXPr - 22mg + 17mg orally For a First Trial, I'm Fairly Impressed 10-24-2019 by Xorkoth 7:20pm (T+0:00) - Weighed out and ate 22mg. I meant to go for 20, but an extra 2mg came out so I went with it. I had an intense work day and feel rather aggravated about it.

Constant Evolution neutral exp #118631

Hello, Today Id like to share a recent experience I have had with 50mg of MXPr (or 3-MeO-2-Oxo-PCPr) orally and in combination with a joint of cannabis later on. Having little information available around on this compound, I had moderate expectations but ended up being quite surprised.

Light Show in the Void neutral exp #113789

Age: 24 Weight: 135 lbs Dosage: 60 mg Intranasal Setting: My apartment T0:00- Dose administered, a fairly large quantity of powder which is very light and fluffy. It stings a good bit initially but this quickly fades to an aching discomfort. After about 1 minute its really not too bad at all.

MXPr = MXE Squared neutral exp #113720

Today is the second day of a 2-day binge wherein I took a grand total of 500mg. The MXPr has all been long since consumed, I am now, at 20 hours after ingestion, still in the process of coming down, and comfortably so.

A *Pr*operly Mextifying View of Reality neutral exp #115640

How might an oak see the world? How might a ladybug? If you could consolidate the mycelial net of a mile-wide fungal colony and put it in a two-legged body, how might its perceptions differ from yours? Imagine if it had access to the knowledge, the understanding that youve gathered through your years on Earth, but vie...

Pleasant Warmth Meets Plain Dissociation neutral exp #115014

Setting: At home, in my bed Tolerance: Maybe a little, but not much (I use dissos 1-2 p. month on average). Last experience was a k-hole 17 days ago. Prior disso experience: R,S-ketamine: 25x (at least) // 2-FDCK: 5x // DCK: 5x // Nitrous Oxide: 5x // DXM (low dose): 3x // 3-MeO-PCE: 2x // 3-MeO-PCP: 1x No substa...

Repetitive Nonsense neutral exp #114806

I feel I owe a report on this novel dissociative since there is such little info. It started on a Wednesday. I first tried 30mg insufflated to see if the reports of potency were wrong. Minor dissociation starts at +20 minutes. It is very functional at this point. Hard to tell if I'm even on a substance or not.

Bluelight 4 threads 3 neutral 1 cautionary visit

Mxpr 22mg 17mg Oral First Time For A First Trial Im Fairly Impressed neutral

3-MeO-2'-oxo-PCPr / MXPr - 22mg + 17mg orally For a First Trial, I'm Fairly Impressed 10-24-2019 by Xorkoth 7:20pm (T+0:00) - Weighed out and ate 22mg. I meant to go for 20, but an extra 2mg came out so I went with it. I had an intense work day and feel rather aggravated about it.

Mxpr 60 Mg Intranasal First Time Light Show In The Void neutral

Age: 24 Weight: 135 lbs Dosage: 60 mg Intranasal Setting: My apartment T0:00- Dose administered, a fairly large quantity of powder which is very light and fluffy. It stings a good bit initially but this quickly fades to an aching discomfort. After about 1 minute its really not too bad at all.

Mxpr 250 Mg Total Oral First Trial Airy Invigorating Superficially Revelatory neutral

MXPr (250 mg total, oral) - First time - Airy, invigorating, superficially revelatory 14 November, 2019 I recently obtained a small sample of MXPr, a novel dissociative that I've been hearing a little bit about for a while.

Mxpr 200mg Plugged First Time Messed Up Big Time On Mxpr cautionary

Ive posted this elsewhere on bluelight, but as requested, here it is copy and pasted into the trip reports forum: So.... I'm a god damn idiot. I fucked up big time with this chem. This is not a warning so much as a tale of stupidity. A long tale. I've just finished writing it and its definitely a tl;dr.

Bluelight Reference Guide Bluelight

Dissociatives The Big and Dandy 3-MeO-2-oxo-PCPr (MXPr) Thread

I just received word from what promises to be a reliable source (there are reasons to not doubt this is true) that 3-MeO-2-oxo-PCPr, that is, MXE with a PCPr base instead of a PCE base, will be released in the near future.

Read full thread on Bluelight →

Methoxpropamine's nerd page Pharmacology, chemical data, effect profiles, and more

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Helpful Links

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Methoxpropamine Encyclopedic Encyclopedic Typical encyclopedia coverage. Cross-reference for important decisions. 2 corroborating sources 1 ROA with full dose ladder duration data present 18 combo interactions documented dose data not in PW/TripSit (unverifiable)