Methoxypiperamide
Summary
Drug of the Piperazine class. The 4-Methoxy-ฮฑ-keto analogue of Methylbenzylpiperazine. Seemingly inactive on its own.
Effect Profile
Scores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Opioid
1.9
Light
2/10
Low sedation
Euphoria / Warmth
×3
0
Analgesia
×2
0
Sedation / Relaxation
×1
3
sedation
Itching / Nausea
×1
0
Based on reports from:
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7โ14 days for partial reset; full reset may take weeks โ tolerance loss greatly increases overdose risk
Tolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~35d
Effects
Negative
- Motor impairment
- Sedation
Positive
- Reduced anxiety
Neutral
- Dulled perception
Combinations
Methoxypiperamide's nerd page
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