Methylnaphthidate Stats & Data
COC(=O)C(C1CCCCN1)c1ccc2ccccc2c1DNRNSIJBSCBESJ-UHFFFAOYSA-NPharmacology
DrugBankReceptor Profile
Receptor Actions
Toxicity
PsychonautWikiThe toxicity and long-term health effects of recreational methylnaphthidate use do not seem to have been studied in any scientific context and the exact toxic and lethal dosages are unknown. This is because methylnaphthidate is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried methylnaphthidate suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). [https://www.google.com Independent research]should always be done to ensure that a combination of two or more substances is safe before consumption. It is strongly recommended that one use harm reduction practices when using this drug.
Effect Profile
Curated + 4 ReportsStrong anxiety/jitters and focus with mild stimulation and euphoria
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 4 experience reports (4 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 1
Adverse Effects 0
Real-World Dose Distribution
62K DosesFrom 8 individual dose entries
Insufflated (n=6)
Form / Preparation
Most common forms and preparations reported
Legal Status
| Country | Status | Notes |
|---|---|---|
| Germany | HDMP-28 is controlled under the NpSG ( New Psychoactive Substances Act ) as of November 26, 2016. | Production and import with the aim to place it on the market, administration to another person and trading is punishable. Possession is illegal but not penalized. |
| Switzerland | HDMP-28 is illegal | |
| Turkey | HDMP-28 is illegal in Turkey as of February 2016. | |
| United Kingdom | HDMP-28 is a class B drug in the UK as of 31st May 2017 and is illegal to possess, produce or supply. | |
| United States | HDMP-28 is not explicitly controlled in the US, but it could possibly be considered an analog of a Schedule II substance (methylphenidate) under the Federal Analog Act. |
References
Data Sources
Cited References
- Bluelight: HDMP-28 or Methylnaphthidate Discussion Thread
- Bluelight: New Stimulant Methylnaphthidate Thread
- Davies et al. 2004: Synthesis of methylphenidate analogues and their binding affinities
- Drugs-Forum: HDMP-28 Wiki
- Erowid: HDMP-28 Experience Vault
- Gillman 2005: Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity
- Lile et al. 2003: The reinforcing efficacy of psychostimulants in rhesus monkeys
- Talaie et al. 2009: Dose-independent occurrence of seizure with tramadol
- TripSit: HDMP-28 Factsheet