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    MMDA molecular structure

    MMDA Stats & Data

    NPS DataHub
    MW209.25
    FormulaC11H15NO3
    CAS13674-05-0
    IUPAC1-(7-Methoxy-1,3-benzodioxol-5-yl)propan-2-amine
    SMILESCOc1cc(CC(C)N)cc2OCOc12
    InChIKeyYQYUWUKDEVZFDB-UHFFFAOYSA-N
    Phenethylamines
    Chemical Class Substituted amphetamine
    Psychoactive Class Stimulant / Psychedelic / Entactogen

    Pharmacology

    DrugBank
    State Solid

    Description

    MMDA, or 3-methoxy-4,5-methylenedioxyamphetamine, is a member of the amphetamine drug class with stimulant and psychedelic properties. It also acts as an entheogen and an entactogen. MMDA bears resemblance to the psychopharmacologically active essential oils elemicin and myristicin found in nutmeg. The effects of MMDA includes feelings of euphoria and warmth, as well as realistic closed-eye visuals.

    Mechanism of Action

    The mechanism that produces the psychedelic activity of MMDA has not been definitively established. There are, as of the present time, no reported studies on the human pharmacokinetics or metabolism of MMDA. Based on its structural relationship with other similar drugs for which the pharmacology is known, it is likely that MMDA has multiple mechanisms of action, and probably acts both as a 5HT2A agonist in a similar manner to hallucinogenic amphetamines such as DOM, and also as a serotonin releaser by reversing the direction of the serotonin reuptake transporter in a similar manner to MDMA.

    Indication

    MMDA is a recreational drug. It has no current medical uses and is a Schedule I controlled substance in the USA at present.

    Effect Profile

    Curated + 4 Reports
    Psychedelic 2.1

    Mild visuals with strong body load, low headspace

    Visual Intensity×3
    4
    Headspace Depth×3
    1
    Auditory Effects×1
    0
    Body Load / Somatic Effects×1
    8
    Empathogen 5.0

    Strong sensory enhancement and euphoria with moderate stimulation

    Empathy / Social Openness×3
    0
    Euphoria / Mood Elevation×2
    9
    Stimulation×1
    7
    Sensory Enhancement×1
    10
    Stimulant 6.5

    Strong euphoria with strong anxiety/jitters, moderate focus and stimulation

    Stimulation / Energy×3
    6
    Euphoria / Mood Lift×2
    10
    Focus / Productivity×2
    7
    Anxiety / Jitters×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 1d Half tolerance 10d Baseline ~18d

    Experience Report Analysis

    Erowid
    5 Reports
    4 Single-substance
    2010–2023 Date Range
    3 With Age Data
    9 Effects Detected

    Demographics

    Gender Distribution

    Too few reports for a chart: gender is known from 5 reports, and a split is drawn only from 20 reports or more. Counts are shown instead. Why 20?

    • Male 4 of 5
    • Not Specified 1 of 5

    Age Distribution

    Reports Over Time

    Effect Analysis

    Erowid

    Effects aggregated from 4 experience reports (4 single-substance Erowid)

    4 Reports
    9 Effects Detected
    7 Positive
    1 Adverse
    1 Neutral

    Effect Sentiment Distribution

    Confidence Distribution

    Each bar is the share of reports mentioning the effect; its whisker, and the band on the rows below, is the 95% interval: where the share could plausibly be with other reports of the same kind.

    Too few reports for bars: these effects come from 4 single-substance Erowid reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    Positive Effects 7

    Visual Distortions 4 of 4 70%
    Closed-Eye Visuals 4 of 4 70%
    Color Enhancement 4 of 4 70%
    Euphoria 3 of 4 70%
    Introspection 3 of 4 70%
    Empathy 3 of 4 70%
    Music Enhancement 3 of 4 70%

    Adverse Effects 1

    Anxiety 3 of 4 70%
    Show 1 neutral or unclassified mention
    Dissociation 3 of 4

    Form / Preparation

    Most common forms and preparations, as a share of the 4 reports that give one

    Too few reports for bars: these forms come from 4 reports, and a bar is drawn only from 20 reports or more. With fewer, a percentage cannot tell a common effect from a rare one. Counts are shown instead. Why 20?

    • Powder / Crystals 2 of 4
    • Capsule 2 of 4
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