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    Disclaimer
    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.
    ⚠ Opioids carry significant risk of respiratory depression, physical dependence, and fatal overdose. Never combine with other depressants.

    MT-45

    Aliases: Ic-6, mt45

    Depressant Research-chemical Opioid

    Summary TripSit

    A synthetic opioid drug that was rumoured to be roughly 80% the potency of Morphine orally. Was created by Dainippon Pharmaceutical in the 1970's. It has been used as a lead compound for the design of related substances.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral 30-45mg 45-60mg 60mg 60mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 30-45 min 4-6 hrs 2-3 hrs 4.5-6.8 hrs

    Effect Profile

    4 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 6.3
    Strong 6/10

    Strong euphoria with moderate itching/nausea, mild pain relief, low sedation

    Euphoria / Warmth ×3
    10
    physical euphoria euphoria cognitive euphoria mood lift
    Analgesia ×2
    4
    analgesia
    Sedation / Relaxation ×1
    3
    sedation
    ⚠ Itching / Nausea ×1
    7
    nausea constipation dry mouth
    Based on reports from:
    Erowid Experience Reports PsychonautWiki MT-45
    View methodology →

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d

    Effects TripSit

    Positive
    • Analgesia
    • Stimulation
    • Physical euphoria
    Negative
    • Dry Mouth
    • Increased heart rate
    • Nausea
    Neutral
    • Itchiness
    • Relaxant
    • Pupil constriction
    • Sedation
    Positive
    • Euphoria
    • Mood lift
    • Reduced anxiety
    • Cognitive euphoria
    • Anxiety suppression
    Negative
    • Constipation
    • Anxiety
    • Compulsive redosing
    • Dizziness
    Neutral
    • Time distortion
    Positive
    • Increased music appreciation
    • Increased libido
    • Tactile enhancement
    • Color enhancement
    Negative
    • Disinhibition
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    • Double vision
    Neutral
    • Dulled perception

    Combinations TripSit

    MT-45's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TripSit 📖 PsychonautWiki