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    ☠ This is an extremely potent opioid active in microgram doses. Accidental overdose can be rapidly fatal. Naloxone should always be on hand.

    N-(2C)-fentanyl Limited data
    Limited data
    Sparse data. Doses and effects may be unreliable or untested.
    • 2 corroborating sources
    • no dose data
    • 19 combo interactions documented

    Depressant Opioid

    Summary PsychonautWiki

    The N-(2C)-fentanyl series couples the 2C phenethylamines with the fentanyl scaffold. Reported members include N-(2C-B)-, N-(2C-C)-, N-(2C-D)-, N-(2C-E)-, N-(2C-G)-, N-(2C-H)-, N-(2C-I)-, N-(2C-IP)-, N-(2C-N)-, N-(2C-P)-, N-(2C-T)-, N-(2C-T-2)-, N-(2C-T-4)-, N-(2C-T-7)- and N-(2C-TFM)-fentanyl. No human dose, duration or effect data exists for any of them; the profile shown below is class-typical for opioids, not observation of these compounds.

    Effect Profile

    class estimate

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • No reports exist for this substance. Its effect list is the one shared by 8 other substances of the same class, so the scores below describe the class, not this compound.
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Opioid 5.1
    Moderate+ 5/10

    Strong euphoria with moderate itching/nausea, mild sedation

    Euphoria / Warmth ×3
    9
    physical euphoria cognitive euphoria euphoria
    Analgesia ×2
    0
    Sedation / Relaxation ×1
    5
    sedation muscle relaxation
    ⚠ Itching / Nausea ×1
    6
    nausea constipation
    Based on reports from:
    PsychonautWiki N-(2C)-fentanyl
    View methodology →

    Tolerance

    Build-up develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
    Reset 7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~35d

    Effects

    Positive
    • Physical euphoria
    • Muscle relaxation
    • Anxiolytic
    Negative
    • Motor impairment
    • Nausea
    • Respiratory depression
    Neutral
    • Sedation
    • Sedative
    • Dystaxia
    • Itchiness
    Positive
    • Reduced anxiety
    • Anxiety suppression
    • Cognitive euphoria
    • Euphoria
    Negative
    • Dizziness
    • Compulsive redosing
    • Amnesia
    • Thought deceleration
    • Motor control loss
    • Constipation
    Positive
    • Increased music appreciation
    • Increased libido
    Negative
    • Disinhibition
    • Appetite suppression
    • Dehydration
    • Light sensitivity
    • Double vision
    • Acuity suppression
    Neutral
    • Dulled perception
    • Internal hallucinations

    Combinations

    Cross-Check N-(2C)-fentanyl with another substance

    N-(2C)-fentanyl's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    💊 Pill Identifier 📘 Experience Reports 📖 PsychonautWiki