Summary
One known source in the RC community claims that NDP's potency is 20x stronger than fentanyl. User reports describe pronounced sedation with muted euphoria and an unpleasant 'dirty' body load. Analytical alerts highlight frequent misrepresentation in yellow powders sold as ketamine or pressed pills. Accurate micro-scales and volumetric dosing are mandatory; fentanyl strips may not detect nitazenes.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Peak | Offset | After Effects |
|---|---|---|---|---|
| Oral | 15-30 min | 30 min | 1-3 hrs | 2-4 hrs |
| Insufflated | 5-15 min | 30 min | 1-3 hrs | 2-4 hrs |
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Effects
Positive
- Physical euphoria
- Pain relief
- Muscle relaxation
- Analgesia
Negative
- Respiratory depression
- Nausea
- Itching
- Sedation
- Itchiness
- Pupil constriction
Positive
- Cognitive euphoria
- Anxiety suppression
- Reduced anxiety
- Wakefulness
- Motivation enhancement
- Euphoria
Negative
- Constipation
- Compulsive redosing
- Motivation suppression
- Anxiety
Positive
- Warmth
- Increased music appreciation
- Increased libido
Negative
- Appetite suppression
- Light sensitivity
- Disinhibition
- Dehydration
- Dulled perception
- Warm flush
- Internal hallucination