NEP
Aliases: Ξ-eapp, Ethyl-pentedrone, N-ethylpentedrone, N-ethylnorpentedrone, Ξ-ethylaminopentiophenone
Summary
N-Ethyl-nor-pentedrone (also known as N-Ethylpentedrone, Ethyl-pentedrone or more commonly, NEP) is a lesser-known novel stimulant substance of the cathinone class that produces stimulating, euphoric, and mildly entactogenic effects when administered. The stimulating effects of NEP are believed to mainly be caused by its activity as a norepinephrine-dopamine reuptake inhibitor (NDRI). The reported entactogenic effects it displays may also be due to its activity as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, although new research has shown very low serotonin reuptake inhibition.NEP probably acts as unselective serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 10-25mg | 25-40mg | 40-60mg | 60mg+ |
| Insufflated | 10-20mg | 20-40mg | 40-60mg | 60mg+ |
| Vaporized | 5-15mg | 15-30mg | 30-50mg | 50mg+ |
| Smoked | 5-15mg | 15-30mg | 30-50mg | 50mg+ |
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset |
|---|---|---|---|---|
| Oral | 10-30 min | 15-45 min | 1-2 hrs | 1-2 hrs |
| Insufflated | 5-20 min | 15-30 min | 1-2 hrs | 1-2 hrs |
Effect Profile
6 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Strong sensory enhancement with moderate stimulation and euphoria, low empathy
Strong anxiety/jitters and focus with moderate euphoria, mild stimulation
Tolerance
Cross-Tolerances
Effects
Aggregated from 6 Erowid experience reports