Receptor Profile
Receptor Actions
Effect Profile
Curated + 4 ReportsStrong anxiolysis, cognitive impairment, and euphoria with moderate sedation
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Benzodiazepine tolerance to hypnotic/anxiolytic effects can develop within days to weeks of regular use and decays over weeks with abstinence. Cross‑tolerance across benzodiazepines is expected due to shared GABA(A) positive allosteric modulation; magnitude varies among compounds. Data specific to nimetazepam are limited; figures above are a pragmatic harm‑reduction model rather than clinical PK/PD estimates.
Cross-Tolerances
Experience Report Analysis
ErowidDemographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
ErowidEffects aggregated from 4 experience reports (4 Erowid)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 1
Adverse Effects 0
Real-World Dose Distribution
62K DosesFrom 5 individual dose entries
Legal Status
| Country | Status | Notes |
|---|---|---|
| Hong Kong | regulated under Schedule 1 of Hong Kong's Chapter 134 Dangerous Drugs Ordinance | |
| Singapore | physician prescribed drug, and is regulated under the Misuse of Drugs Act | |
| United States | categorized Schedule IV FDA and DEA |
Harm Reduction
drugs.wikiNimetazepam is marketed mainly in parts of Asia (e.g., as 5 mg 'Erimin 5'); non-medical availability often involves counterfeit tablets that may contain other benzodiazepines, making potency unpredictable—assume unknown composition and avoid mixed-source pills unless lab-checked. Next‑day sedation, impaired coordination, and memory gaps are common with long/medium-acting benzodiazepines; avoid driving or operating machinery until at least the day after use and longer if residual effects are present. Combining benzodiazepines with opioids, alcohol, GHB/GBL, or other depressants greatly increases the risk of life‑threatening respiratory depression and fatal overdose; avoid co‑use and never use alone. Tolerance develops quickly with repeated use and can encourage escalation; spacing uses by weeks and avoiding consecutive‑night dosing reduces risk of rapid tolerance. Abrupt cessation after sustained use can cause severe withdrawal (anxiety, insomnia, agitation, tremor, seizures); any taper should be slow and medically supervised. 'Blackout' amnesia can lead to unintentional redosing—pre‑measure a single dose, keep a log, and have a trusted sober person hold the supply if needed. Crushing or injecting tablets is dangerous due to insoluble binders/fillers (risk of vein damage, infection) and unpredictable kinetics; stick to oral use only. People who are pregnant can produce neonates with benzodiazepine withdrawal symptoms; discuss any exposure with a clinician. Older adults and those with renal or general frailty have heightened sensitivity to sedation and falls; lower thresholds and longer spacing are prudent. Reports note nimetazepam may partially metabolise to nitrazepam and has high oral bioavailability with relatively rapid onset—this can increase misuse potential; extra caution with redosing is warranted. In unregulated markets, prioritize drug checking where available; if not, avoid brand‑dependent assumptions (e.g., 'Erimin 5' logo) as authenticity is unreliable.
References
Data Sources
Cited References
Drugs.wiki References
- Erowid Nimetazepam (Erimin) Vault — names/availability overview
- TripSit Wiki — Uncommon Benzodiazepines (nimetazepam BA, onset ≈30 min, mean half‑life 14–30 h; partial metabolism to nitrazepam)
- PubChem — Nimetazepam compound entry (identity/structure)
- EUDA (EMCDDA) European Drug Report/Overdose risk — benzodiazepines commonly present in fatal overdoses, especially with opioids
- EUDA — Risk factors (polydrug depressant use: opioids + benzodiazepines)
- DrugWise — Benzodiazepines (withdrawal dangers, driving risk, harm‑reduction advice)
- Hi‑Ground — Benzos page (unsafe combinations incl. opioids, alcohol, GHB/GBL, tramadol, ketamine; caution with antipsychotics/antihistamines)
- SubstanceSearch — Nimetazepam alias and rough timing (community HR repository)
- Bluelight — 'Happy 5' / counterfeit 'Erimin 5' discussion (counterfeit prevalence; harm‑reduction context)