Nitemazepam Stats & Data
3-hydroxynimetazepam
NPS DataHub
MW312.3
FormulaC16H14N3O4
CAS40762-03-6
IUPAChydrogen 3-hydroxy-1-methyl-7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
SMILES
O=N(=O)c1ccc2N(C)C(=O)C(O)N=C(c3ccccc3)c2c1.[H+]InChIKey
QRWVNMAJJIQCEG-UHFFFAOYSA-O
Chemical Class
Benzodiazepine
Psychoactive Class
Depressant
History & Culture
Nitemazepam, also known as 3-hydroxynimetazepam, is a benzodiazepine derivative that was originally synthesized during the 1970s. Despite its early development, the compound was never brought to market as a pharmaceutical product. Decades after its initial synthesis, nitemazepam resurfaced as a designer drug within the research chemical market. The substance was first definitively identified in Europe in 2017, representing part of a broader trend of novel benzodiazepines entering grey market circulation.
Effect Profile
Curated
Benzodiazepine
4.7
Strong euphoria with low anxiolysis, sedation, and cognitive impairment
Anxiolysis×3
3
Sedation / Relaxation×2
3
Motor / Cognitive Impairment×1
2
Euphoria / Mood Lift×1
10
Based on reports from:
Tolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Full tolerance
3d
Half tolerance
37d
Baseline
~60d