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    Nitemazepam molecular structure

    Nitemazepam Stats & Data

    Depressant Benzodiazepine
    3-hydroxynimetazepam
    PubChem CID 12362353
    NPS DataHub
    MW312.3
    FormulaC16H14N3O4
    CAS40762-03-6
    IUPAChydrogen 3-hydroxy-1-methyl-7-nitro-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
    SMILESO=N(=O)c1ccc2N(C)C(=O)C(O)N=C(c3ccccc3)c2c1.[H+]
    InChIKeyQRWVNMAJJIQCEG-UHFFFAOYSA-O
    2020/3. Benzodiazepine; 2021/3. Benzodiazepine; 2022/3. Benzodiazepine
    Chemical Class Benzodiazepine
    Psychoactive Class Depressant

    Pharmacology

    DrugBank

    History & Culture

    Nitemazepam, also known as 3-hydroxynimetazepam, is a benzodiazepine derivative that was originally synthesized during the 1970s. Despite its early development, the compound was never brought to market as a pharmaceutical product. Decades after its initial synthesis, nitemazepam resurfaced as a designer drug within the research chemical market. The substance was first definitively identified in Europe in 2017, representing part of a broader trend of novel benzodiazepines entering grey market circulation.

    Effect Profile

    Curated
    Benzodiazepine 4.7

    Strong euphoria with low anxiolysis, sedation, and cognitive impairment

    Anxiolysis×3
    3
    Sedation / Relaxation×2
    3
    Motor / Cognitive Impairment×1
    2
    Euphoria / Mood Lift×1
    10
    Based on reports from:
    Erowid Experience Reports PsychonautWiki Nitemazepam

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 3d Half tolerance 37d Baseline ~60d
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