Summary
Nitrous oxide can cause severe and potentially irreversible vitamin B12 depletion with frequent or chronic use, leading to serious neurological damage including numbness, tingling, and motor control loss. Always supplement with vitamin B12 when using this substance. Never inhale directly from cartridges or tanks due to extreme cold temperature (-40C) which can cause frostbite to lips, throat, and lungs, and high pressure which can rupture lung tissue. Always release gas into a balloon first to warm and depressurize. Ensure adequate oxygen intake between inhalations to prevent hypoxia and brain damage.
Perspectives
“For me, it wasn't a particularly rewarding experience.”
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Inhaled | 4-8g | 8-16g | 16-40g | 40g+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects | Total |
|---|---|---|---|---|---|---|
| Inhaled | 0 min | 0 min | 0 min | 0-6 min | 12-30 min | 1.0-5.0 hrs |
Tolerance
Build-up
develops within a single session with repeated inhalations
Reset
minutes to hours; no lasting tolerance
Effects
Positive
- Physical Euphoria
- Analgesia
- Laughter
- Spontaneous tactile sensations
Negative
- Nausea
- Headaches
- Numbness in extremities
- Sedation
- Reduction of external stimuli
- Buzzing sensation in nerve
- Suggestibility enhancement
Positive
- Cognitive Euphoria
- Laughter Fits
- Giggling
- Mood lift
- Euphoria
- Unity and interconnectedness
Negative
- Motor Control Loss
- Dizziness
- Clumsiness
- Amnesia
- Compulsive redosing
- Depersonalization
- Derealization
- Information processing suppression
- Memory suppression
- Thought deceleration
- Ego Death
- Dissociation
- Time Distortion
- Dream like state
Positive
- Visual Geometry
Negative
- Tactile Suppression
- Acuity suppression
- Auditory suppression
- Double vision
- Frame rate suppression
- Pattern recognition suppression
- Auditory Distortion
- Sound distortion
- Minor to strong hallucinations
- Changes in felt bodily form
- External hallucinations
- Internal hallucinations
- Perception of decreased weight