Nutmeg Stats & Data
Pharmacology
DrugBankDescription
Nutmeg allergenic extract is used in allergenic testing.
Receptor Profile
Receptor Actions
History & Culture
1500 BCE–13th century
Nutmeg is native to the Banda Islands, a cluster of eleven small volcanic islands within the Maluku archipelago of eastern Indonesia. These remote islands remained the world's sole source of both nutmeg and mace until the mid-nineteenth century. Archaeological excavations on Pulau Ai have yielded potsherd residues dating back approximately 3,500 years, representing the earliest known evidence of nutmeg use. The spice circulated through Austronesian maritime trading networks from at least 1500 BCE. By the sixth century CE, nutmeg had spread westward to India and subsequently reached Constantinople. Arab merchants eventually traced the spice to its source in the Banda Islands by the thirteenth century, though they carefully concealed this information from European traders to maintain their commercial advantage.
1511–1945
European pursuit of nutmeg commenced following the Portuguese conquest of Malacca in August 1511. Shortly after securing this strategic trading hub, Afonso de Albuquerque dispatched a three-ship expedition under António de Abreu to locate the legendary spice islands. Malay pilots guided the fleet through Java and the Lesser Sundas, reaching Banda in early 1512. This marked the first European contact with the islands, where the expedition spent approximately one month acquiring nutmeg, mace, and cloves. The Portuguese apothecary Tomé Pires, stationed in Malacca from 1512 to 1515, documented these islands in his work Suma Oriental. However, Portugal never established permanent control over the trade. The Dutch East India Company waged a brutal campaign for monopoly over nutmeg production in 1621. The violence was catastrophic for the indigenous Bandanese population—historians estimate that of approximately 15,000 inhabitants, only around 1,000 survived, with the remainder killed, starved during flight, exiled, or sold into slavery. The Company subsequently constructed extensive plantation systems throughout the islands. During the Napoleonic Wars, British forces temporarily occupied the Banda Islands and transplanted nutmeg trees, along with their native soil, to Ceylon, Penang, Bencoolen, and Singapore. From these locations, cultivation spread to additional colonial territories including Zanzibar and Grenada. Dutch control of the Spice Islands persisted until the Second World War.
Nutmeg has acquired symbolic importance in several regions shaped by its trade history. Grenada, which developed into a major producer following British colonial transplantation efforts, incorporated a stylized split-open nutmeg fruit into its national flag upon adoption in 1974. In the United States, Connecticut carries the nickname "the Nutmeg State," purportedly stemming from folklore about dishonest traders who carved wooden imitations to deceive buyers. The expression "wooden nutmeg" subsequently entered American vernacular as a general term for fraudulent merchandise. Beyond culinary applications, nutmeg has traditionally been consumed for its psychoactive and reputed aphrodisiac properties, though clinical evidence supporting these uses remains limited. Its widespread availability and low cost have led to recreational experimentation, particularly among adolescents, college students, and incarcerated individuals seeking inexpensive intoxication.
Effect Profile
Curated + 392 ReportsStrong visuals, auditory effects, and body load with low headspace
Empirical Duration
Erowid ReportsTolerance & Pharmacokinetics
drugs.wikiTolerance Decay
Demographics
Gender Distribution
Age Distribution
Reports Over Time
Effect Analysis
Erowid + BluelightEffects aggregated from 392 experience reports (377 Erowid + 15 Bluelight)
Effect Sentiment Distribution
Confidence Distribution
Positive Effects 35
Adverse Effects 34
Subjective Effect Ontology
Experience ReportsStructured effect tags extracted from 392 Erowid & Bluelight experience reports using a controlled vocabulary of 220+ canonical effects across 15 domains.
Auditory
Emotional
Gastrointestinal
Motor
Visual
Dosage Distribution
Dose distribution from experience reports
Real-World Dose Distribution
62K DosesFrom 448 individual dose entries
Oral (n=130)
Common Combinations
Most co-occurring substances in experience reports
Form / Preparation
Most common forms and preparations reported
Body-Weight Dosing
Dose relative to body weight from reports with weight data
Redose Patterns
Redosing behavior across 311 reports
References
Data Sources
Cited References
- ChemSpider: Myristicin Chemical Structure
- Erowid: Nutmeg Basics
- Erowid: Nutmeg Effects & Chemistry
- Erowid: Nutmeg FAQ
- Erowid: Nutmeg Vault
- El-Alfy et al. 2019: Phenolic compounds from nutmeg inhibit FAAH
- El-Alfy et al. 2016: Indirect modulation of endocannabinoid system by nutmeg
- Healthline: High on Nutmeg - Effects and Dangers
- IsomerDesign: Myristicin Drug Status Report
- NCATS: Myristicin Drug Profile
- Project CBD: Chemicals in Nutmeg Boost Anandamide
- PsychonautWiki: Myristicin
- PubChem: Myristicin Compound Summary
- Wikipedia: Myristicin
- Wikipedia: Myristica fragrans
- DrugWise: Nutmeg