Summary
Nutmeg contains myristicin and other phenylpropenes (elemicin, safrole) that produce deliriant and cannabimimetic effects. The potency varies significantly between batches; fresh whole seeds are more potent than pre-ground powder which degrades over time. Effects are often described as unpleasant with severe nausea, intense dry mouth, tachycardia, and prolonged hangover lasting up to 48 hours. At doses above 5g, risk of acute toxicity increases substantially. Myristicin works primarily by inhibiting FAAH and MAGL enzymes, indirectly boosting endocannabinoid levels rather than directly binding to cannabinoid receptors.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Oral | 2-7 hrs | 1-4 hrs | 8-12 hrs | 12-48 hrs | 12 hrs |
Tolerance
Build-up
develops over weeks of regular use via CB1 receptor downregulation
Reset
2–4 weeks for most users; heavy users may need longer
Effects
Positive
- Muscle relaxation
- Stimulation
Negative
- Nausea
- Dry mouth
- Ataxia
- Sedation
- Difficulty urinating
- Bloodshot eyes
- Sleepiness
- Muscle twitches
Positive
- Cognitive euphoria
Negative
- Anxiety
- Paranoia
- Delirium
- Disorientation
- Dizziness
- Memory impairment
- Confusion
- Analysis suppression
- Time distortion
Positive
- Tactile enhancement
- Appetite enhancement
- Tracers
- Colour shifting
Negative
- Visual acuity suppression
- Environmental patterning
- Drifting
- Visual distortions
- Internal hallucination
- External hallucination