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    O-PCPr Stats & Data

    2'-oxo-pcpr Deschloro-n-propyl-ketamine
    Psychoactive Class Dissociative
    Half-Life Unknown in humans; treat as unknown—do not assume short clearance due to lingering after‑effects in reports.

    Effect Profile

    Curated + 2 Reports
    Dissociative 6.3

    Strong dissociative depth and motor impairment with moderate mania, mild insight

    Dissociative Depth×3
    10
    Mania / Compulsion×1
    6
    Insight / Novel Thought×2
    5
    Motor / Sensory Impairment×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki
    Half-Life
    Unknown in humans; treat as unknown—do not assume short clearance due to lingering after‑effects in reports.
    Addiction Potential
    Moderate-to-high: dissociatives in this class show psychological reinforcement with binges and difficulty spacing use; several weeks may be needed to restore baseline response.

    Tolerance Decay

    Full tolerance 1d Half tolerance 7d Baseline ~21d

    Anecdotal reports with arylcyclohexylamines suggest rapid acute tolerance within a session and slow decay over 2–4+ weeks; spacing multi‑week intervals helps restore baseline response.

    Cross-Tolerances

    Ketamine
    50% ●○○
    O-PCE
    50% ●○○
    3-MeO-PCP and PCP analogs
    50% ●○○

    Experience Report Analysis

    Erowid
    2 Reports
    2025–2025 Date Range
    2 With Age Data

    Demographics

    Gender Distribution

    Age Distribution

    Reports Over Time

    Harm Reduction

    drugs.wiki

    Identity and naming: O‑PCPr is 2′‑Oxo‑PCPr (2‑keto‑PCPr), an arylcyclohexylamine closely related to O‑PCE and PCP analogs; community threads reported it emerging after late‑2024 mislabeling as O‑PCE/O‑PCP. Mislabeling is common in this class—use drug checking and perform an allergy test before any psychoactive dose. Community reports describe a short‑to‑moderate duration dissociative with heavy body load, motor incoordination, and intermittent euphoria; sensitivity varies widely, so start low and wait a full onset window (at least 60–120 minutes oral, 45–60 minutes IN) before considering any redose. Dissociatives can aggravate lower urinary tract symptoms; ketamine‑like urological complications (including cystitis) are dose/frequency‑related—prioritize spacing (≥2–4 weeks), hydration, and early cessation if urinary discomfort, urgency, or pain occurs. Combining dissociatives with other CNS depressants (alcohol, benzos, GHB/GBL) markedly increases risks of blackout, aspiration, and accidents; stimulants raise cardiovascular strain and can precipitate agitation or manic states; avoid tramadol due to seizure risk and serotonergic complications. Use precise measurement: 0.001 g scales and volumetric dosing reduce dosing error and support allergy testing (e.g., ≤1 mg) when a lab result is unavailable. Expect impaired coordination and lingering fog; do not drive or perform safety‑critical tasks until fully baseline the next day. Market reports have noted bladder irritation and supply confusion (e.g., O‑PCE or O‑PCP sold instead); reagent tests are insufficient—seek lab‑based drug checking where available.

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