Summary
O-PCPr emerged in late 2024 after being mis-sold as O-PCE. User reports describe a steep dose-response curve, rapid onset with upwellings of euphoria, pronounced motor incoordination, bright closed-eye visuals, and a warm euphoria distinct from MXiPr or O-PCE. The headspace is relatively lucid and functional compared to other dissociatives. Analytical work (HR-MS, GC-MS) has begun mapping 2-oxo-PCPr metabolites, but no peer-reviewed human pharmacokinetics exist. Some users report bladder and urinary irritation.
Dose Information
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | After Effects |
|---|---|---|---|---|---|
| Insufflated | 5-15 min | 10-20 min | 1-3 hrs | 2-4 hrs | 1-4 hrs |
| Oral | 30-60 min | 30-60 min | 1-3 hrs | 2-4 hrs | 1-4 hrs |
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Effects
Positive
- Analgesia
- Physical euphoria
- Stimulation
- Pain relief
Negative
- Numbness
- Loss of balance
- Nausea
- Physical disconnection
- Suggestibility enhancement
- Sedation
Positive
- Euphoria
- Conceptual thinking
- Analysis enhancement
- Cognitive euphoria
Negative
- Cognitive disconnection
- Motor control loss
- Amnesia
- Depersonalization
- Derealization
- Time distortion
Positive
- Perception of bodily lightness
- Increased music appreciation
- Tactile enhancement
Negative
- Spatial disorientation
- Tactile suppression
- Disinhibition
- Double vision
- Visual disconnection
- Internal hallucination
- Auditory distortion