I ordered 10g of Oxiracetam from an online distributor and received it in a silver foil packet about four days later. The substance is crystalline and looks much like sugar. Dissolves instantly in water with very little taste or odor (Princess Bride anyone?). The initial effects were incredible for me in particular.
Oxiracetam
Well-documented
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Well-documented
Multiple authoritative sources agree on dosing and effects.
- 6 corroborating sources
- 1 ROA with full dose ladder
- duration data present
- PubChem toxicity data
Aliases: Ct-848, Isf 2522, Neuromet, Neuractiv, Cgp-21690e, hydroxypiracetam
Summary
Oxiracetam (ISF 2522) is a mild central nervous system stimulant and nootropic agent belonging to the racetam family of drugs. Although it is one of the first known and synthesized derivatives of piracetam, its research and efficacy in humans is limited. Oxiracetam is readily available and sold through online vendors as a dietary supplement in the United States.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 500-1200mg | 1200-1800mg | 1800-2400mg | 2400mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-90 min | 30-60 min | 2-4 hrs | 2-4 hrs | 4-6 hrs |
Effect Profile
7 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Stimulant
7.0
Strong+
7/10
Strong focus and stimulation with low euphoria and anxiety/jitters
Stimulation / Energy
×3
8
stimulation
stamina enhancement
wakefulness
mild stimulation
Euphoria / Mood Lift
×2
2
motivation enhancement
Focus / Productivity
×2
10
focus enhancement
cognitive clarity
analysis enhancement
memory enhancement
motivation enhancement
Anxiety / Jitters
×1
2
increased heart rate
Based on reports from:
Tolerance
Build-up
develops over days to weeks of regular use
Reset
3–7 days for acute tolerance; longer for full reset
Tolerance Decay
Full tolerance
14d
Half tolerance
7d
Baseline
~30d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Tolerance appears to build gradually with frequent daily use and decays over weeks after cessation, based on user patterns with racetams generally; consider cycling (e.g., 5 days on, 2 off, or 2–4 weeks on, 1–2 weeks off) to maintain effect and reduce escalation. Data are anecdotal.
Cross-Tolerances
Effects
Aggregated from 7 Erowid experience reports
Positive Effects 3
Euphoria
42.9%
70%
Stimulation
42.9%
70%
Focus Enhancement
42.9%
70%
Adverse Effects 0
Community Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.
Erowid 1 report 1 neutral visit
Oxiracetam's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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