Oxytocin
Aliases: Pitocin, Syntocinon
Summary
Oxytocin is a hormone associated with parenting and social bonding. It is released after birth in women and after orgasm in both sexes. Oxytocin is sometimes administered to facilitate labor or lactation.
Effect Profile
8 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Opioid
5.1
Moderate+
5/10
Strong euphoria with moderate itching/nausea, mild sedation
Euphoria / Warmth
×3
9
physical euphoria
cognitive euphoria
euphoria
Analgesia
×2
0
Sedation / Relaxation
×1
5
sedation
muscle relaxation
Itching / Nausea
×1
6
nausea
constipation
Based on reports from:
Tolerance
Build-up
develops within days of regular use; analgesic tolerance faster than respiratory depression tolerance
Reset
7–14 days for partial reset; full reset may take weeks — tolerance loss greatly increases overdose risk
Tolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~35d
Effects
Aggregated from 8 Erowid experience reports
Positive Effects 2
Euphoria
37.5%
70%
Empathy
37.5%
70%
Adverse Effects 0
Combinations
Oxytocin's nerd page
Pharmacology, chemical data, effect profiles, and more
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