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    Paracetamol Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 3 corroborating sources
    • partial dose data
    • duration data present
    • PubChem toxicity data

    Aliases: Apap, Tylenol, Acetaminophen, Pain reliever extra strength

    Summary Erowid TripSit

    Acetaminophen is a non-salicylate analgesic and antipyretic (pain killer and fever reducer). It is a common over-the-counter pain medication found in hundreds of products around the world. At higher doses it is known to cause liver-damage and has a low therapeutic index (ratio of effective dose to toxic dose), making it dangerous when included in recreationally used pharmaceuticals.

    Dose Information TripSit

    ROA Light Common Strong Heavy
    Oral - 200-500mg - -
    Light Common Strong Heavy

    Onset, Duration & After-effects TripSit

    ROA Onset Peak After Effects Total
    Oral 60 min 4-6 hrs 1-2 hrs 4-6 hrs

    Add to PsychonautWiki Journal

    The PsychonautWiki Journal logging app doesn't include every substance. To track Paracetamol there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:

    Name
    Paracetamol
    Unit
    mg
    Description 
    Paracetamol
Source: SubstanceSearch (substancesearch.com)

Oral dose (mg): common 200-500

Oral duration: onset 1h · peak 4-6h · total 4-6h · after-effects 1-2h

Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.

    Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 350 mg (Oral).

    The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.

    Tolerance

    Build-up varies by mechanism; therapeutic tolerance may develop over weeks of regular use
    Reset typically days to weeks after discontinuation

    Tolerance Decay

    Full tolerance 3d Half tolerance 8d Baseline ~14d

    Effects Erowid

    Aggregated from 32 Erowid experience reports

    Positive Effects 7

    Euphoria 46.9% 70%
    Stimulation 31.2% 70%
    Empathy 18.8% 70%
    Music Enhancement 15.6% 70%
    Tactile Enhancement 15.6% 70%
    Body High 15.6% 70%
    Focus Enhancement 12.5% 70%

    Adverse Effects 6

    Anxiety 40.6% 70%
    Nausea 37.5% 70%
    Headache 31.2% 70%
    Motor Impairment 15.6% 70%
    Increased Heart Rate 12.5% 70%
    Muscle Tension 9.4% 70%

    Pill Identifiers

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    Helpful Links

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