Parafluorofentanyl
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Tentative
- 1 source
- 1 ROA with full dose ladder
- duration data present
- 19 combo interactions documented
- classified Tentative
Aliases: Pff, 4-fluorofentanyl
Summary
Rare, little known and extremely potent analogue of Fentanyl developed by Janssen Pharmaceutica in the 1960s. Use with extreme caution and never mix with other depressants.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Insufflated | 10-25ug | 25-40ug | 40-65ug | 65ug+ |
Onset, Duration & After-effects
| ROA | Onset | Peak |
|---|---|---|
| Insufflated | 0-1 min | 2-3 hrs |
Effect Profile
class estimateScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- No reports exist for this substance. Its effect list is the one shared by 1 other substance of the same class, so the scores below describe the class, not this compound.
- Weighted by importance: core (×3), major (×2), minor (×1)
Moderate euphoria with mild itching/nausea, low sedation
Add to PsychonautWiki Journal
The PsychonautWiki Journal logging app doesn't include every substance. To track Parafluorofentanyl there, start adding an ingestion, search for the name, and choose to add it as a custom substance. Paste these values:
Parafluorofentanyl Source: SubstanceSearch (substancesearch.com) Insufflated dose (µg): light 10-25ug · common 25-40ug · strong 40-65ug · heavy 65ug+ Insufflated duration: onset 0-1m · peak 2-3h · after-effects 1-2h Note: ranges are harm-reduction guidance, not a prescription. Start low, go slow, and test your substances.
Tip: for quicker logging you can also add a Custom Unit in the app, e.g. common dose ~ 32.5 µg (Insufflated).
The app keeps custom substances simple, so the full dose ranges live in the description text above. Ranges are harm-reduction guidance, not a prescription.
Tolerance
Tolerance Decay
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
- Stimulation
- Motor impairment
- Increased heart rate
- Insomnia
- Nausea
- Vasoconstriction
- Restlessness
- Sedation
- Decreased appetite
- Reduced anxiety
- Euphoria
- Cognitive euphoria
- Wakefulness
- Empathy
- Anxiety
- Confusion
- Compulsive redosing
- Time distortion
- Talkativeness
- Increased music appreciation
- Color enhancement
- Tactile enhancement
- Brightened colour
- Light sensitivity
- Appetite suppression
- Dehydration
- Disinhibition
- Dulled perception
- Drifting
Combinations
Cross-Check Parafluorofentanyl with another substanceHelpful Links
Report an issue or suggest an edit
Spotted incorrect or dangerous information, have a correction, a new study, or a useful addition for Parafluorofentanyl? Let us know. Reports are reviewed by moderators — this is not posted publicly.