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    ๐Ÿงช This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    PCE Encyclopedic
    Encyclopedic
    Typical encyclopedia coverage. Cross-reference for important decisions.
    • 4 corroborating sources
    • 3 ROAs with full dose ladders
    • duration data present
    • 18 combo interactions documented
    • PubChem toxicity data
    • classified Tentative
    • classified Research-chemical

    Aliases: Ci-400, Eticyclidine, Cyclohexamine

    Summary TheDrug.Wiki TripSit PsychonautWiki

    PCE is a potent dissociative that causes psychosis and mania at significantly higher rates than other dissociatives. Users should avoid taking the drug multiple days in a row or in high doses. Volumetric liquid dosing is strongly recommended due to the drug's extreme potency, as most standard milligram scales cannot accurately weigh doses below 10-15 mg.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 3-5mg 5-10mg 10-15mg 15mg+
    Insufflated 2-4mg 4-8mg 8-15mg 15mg+
    Smoked 2-4mg 4-8mg 8-12mg 12mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-90 min 30-60 min 2-3 hrs 1-2 hrs 4-48 hrs 2-5 hrs
    Insufflated 19-60 min 30-45 min 2-3 hrs 1-2 hrs 4-48 hrs 2-5 hrs
    Smoked 30-90 min 30-60 min 2-3 hrs 1-2 hrs 4-48 hrs 2-5 hrs

    Effect Profile

    3 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 6.6
    Strong+ 7/10

    Strong dissociative depth, mania, motor impairment, and insight

    Dissociative Depth ×3
    10
    consciousness disconnection depersonalization derealization physical disconnection visual disconnection spatial disorientation +1 more
    Mania / Compulsion ×1
    10
    mania compulsive redosing thought acceleration disinhibition stimulation
    Insight / Novel Thought ×2
    8
    conceptual thinking introspection creativity enhancement immersion enhancement
    Motor / Sensory Impairment ×1
    10
    motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2โ€“4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Effects Erowid

    Aggregated from 3 Erowid experience reports

    Positive Effects 2

    Empathy 100.0% 70%
    Music Enhancement 100.0% 70%

    Adverse Effects 1

    Anxiety 100.0% 70%

    Combinations TripSit

    Cross-Check PCE with another substance

    Community Trip Reports

    Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance.

    Erowid 3 reports 2 neutral 1 cautionary visit
    Bioassay: Eight Human Trials With Eticyclidine neutral exp #116855

    **Background information** - gender: male - age: 24 - weight: 80 kg - setting: at home - set: feeling great today - tolerance: none, I use dissociatives approx. once or twice a month (I made an exception for this titration and used a little more frequently than usual).

    Psychestim
    Really Difficult to Describe neutral exp #112776

    I t's very similar to PCP. I usually synthesize my drugs myself, can't get the precoursers for PCP, but I can easily get them for PCE, so I thought "close enough" and went with that.

    theAngryLittleBunny
    The Weirdest and Maybe Worst Addiction I Had cautionary exp #114164

    The addiction to dissociative drugs is very strange. I've tried many drugs before PCE, which are Mephedrone, Methcathinone, Methamphetamine, benzos and some barbiturates, tramadol and probably a few others.

    theAngryLittleBunny · 2 - 50 mg oral
    Bluelight 3 threads 3 neutral visit
    3 Me Pce 15 Mg Intranasal Experienced The Electric Fog neutral

    Age: 26 Weight: 130 lbs Dosage: 15 mg intranasal Setting: My house Here is an overall summary of this drug that I wrote. This is a detailed report of a single experience. Preface: The design for 3-Me-PCE is a straightforward low-risk bet for an active arylcyclohexylamine.

    scraped 2026-03-14
    Pce 5 Mg First Time Overlooked Curiousity neutral

    [Retrospective note: This report was written while partially under the influence. PCE most definitely has an ego-inflating aspect. Please keep this in mind while reading my somewhat self-loving report.] It is truly unfortunate that there is so little information available on Arylcyclohexamines, as somewhere between Ket...

    scraped 2026-03-14
    2 Keto Pce First Time Methoxetamines Retarded Cousin neutral

    This is basically Tiletamine with a phenyl instead of a thienyl ring. I got the chance to try this one. I was *extremely* excited as it is the closest we have to a Ketamine analogue (but still very far)...

    scraped 2026-03-14

    Bluelight Reference Guide Bluelight

    Dissociatives The Small & Handy PCE (Eticyclidine) Thread

    I wanted to start one of these "Small & Handy" threads for a long time and it seems now is the time because I might receive a yet unknown quantity of this rare dissociative.

    Read full thread on Bluelight โ†’

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