**Background information** - gender: male - age: 24 - weight: 80 kg - setting: at home - set: feeling great today - tolerance: none, I use dissociatives approx. once or twice a month (I made an exception for this titration and used a little more frequently than usual).
PCE
Encyclopedic
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Encyclopedic
Typical encyclopedia coverage. Cross-reference for important decisions.
- 4 corroborating sources
- 3 ROAs with full dose ladders
- duration data present
- 18 combo interactions documented
- toxicity data (PsychonautWiki)
- classified Tentative
- classified Research-chemical
Aliases: Ci-400, Eticyclidine, Cyclohexamine
Summary
PCE is a potent dissociative that causes psychosis and mania at significantly higher rates than other dissociatives. Users should avoid taking the drug multiple days in a row or in high doses. Volumetric liquid dosing is strongly recommended due to the drug's extreme potency, as most standard milligram scales cannot accurately weigh doses below 10-15 mg.
Dose Information
| ROA | Light | Common | Strong | Heavy |
|---|---|---|---|---|
| Oral | 3-5mg | 5-10mg | 10-15mg | 15mg+ |
| Insufflated | 2-4mg | 4-8mg | 8-15mg | 15mg+ |
| Smoked | 2-4mg | 4-8mg | 8-12mg | 12mg+ |
Light
Common
Strong
Heavy
Onset, Duration & After-effects
| ROA | Onset | Comeup | Peak | Offset | Total |
|---|---|---|---|---|---|
| Oral | 30-90 min | 30-60 min | 2-3 hrs | 1-2 hrs | 2-5 hrs |
| Insufflated | 19-60 min | 30-45 min | 2-3 hrs | 1-2 hrs | 2-5 hrs |
| Smoked | <1-2 min | 30-60 min | - | 1-2 hrs | 2-5 hrs |
Effect Profile
3 reportsScores (1–10) curated from multiple sources:
- Effect keyword matching from PsychonautWiki catalog
- Weighted by importance: core (×3), major (×2), minor (×1)
Dissociative
6.6
Strong+
7/10
Strong dissociative depth, mania, motor impairment, and insight
Dissociative Depth
×3
10
consciousness disconnection
depersonalization
derealization
physical disconnection
visual disconnection
spatial disorientation
+1 more
Mania / Compulsion
×1
10
mania
compulsive redosing
thought acceleration
disinhibition
stimulation
Insight / Novel Thought
×2
8
conceptual thinking
introspection
creativity enhancement
immersion enhancement
Motor / Sensory Impairment
×1
10
motor control loss
physical disconnection
tactile suppression
numbness
spatial disorientation
visual disconnection
Based on reports from:
Import into PsychonautWiki Journal
The PsychonautWiki Journal app includes PCE, but its built-in data can be thinner than ours. Importing this file adds a separate "PCE (Substance Search)" custom substance with our dose ranges, durations and tolerance, so you can log against whichever you prefer.
⬇ Download import file
Import this file as custom substances
and you get "PCE (Substance Search)" with every
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Android (v15+); the format is confirmed by the app's
developer.
Ranges are harm-reduction guidance, not a prescription.
Tolerance
Build-up
develops with repeated use over days to weeks
Reset
2–4 weeks for noticeable reduction
Tolerance Decay
Full tolerance
1d
Half tolerance
21d
Baseline
~28d
Acute tolerance: develops within a single session — the reset numbers above apply after sustained heavy use, not after one binge. Within-session tachyphylaxis usually resets largely overnight.
Effects
Aggregated from 3 Erowid experience reports
Positive Effects 2
Empathy
100.0%
70%
Music Enhancement
100.0%
70%
Adverse Effects 1
Anxiety
100.0%
70%
Combinations
Cross-Check PCE with another substanceCommunity Trip Reports
Anecdotal first-person accounts from Reddit, Erowid, and Bluelight. Click a source to expand. Reports are harm-reduction context, not medical guidance. Tags summarise each author's own verdict — how reports are classified.
Erowid 3 reports 2 neutral 1 cautionary visit
I t's very similar to PCP. I usually synthesize my drugs myself, can't get the precoursers for PCP, but I can easily get them for PCE, so I thought "close enough" and went with that.
The addiction to dissociative drugs is very strange. I've tried many drugs before PCE, which are Mephedrone, Methcathinone, Methamphetamine, benzos and some barbiturates, tramadol and probably a few others.
Bluelight 3 threads 3 neutral visit
Age: 26 Weight: 130 lbs Dosage: 15 mg intranasal Setting: My house Here is an overall summary of this drug that I wrote. This is a detailed report of a single experience. Preface: The design for 3-Me-PCE is a straightforward low-risk bet for an active arylcyclohexylamine.
[Retrospective note: This report was written while partially under the influence. PCE most definitely has an ego-inflating aspect. Please keep this in mind while reading my somewhat self-loving report.] It is truly unfortunate that there is so little information available on Arylcyclohexamines, as somewhere between Ket...
This is basically Tiletamine with a phenyl instead of a thienyl ring. I got the chance to try this one. I was *extremely* excited as it is the closest we have to a Ketamine analogue (but still very far)...
Bluelight Reference Guide
Dissociatives The Small & Handy PCE (Eticyclidine) Thread
I wanted to start one of these "Small & Handy" threads for a long time and it seems now is the time because I might receive a yet unknown quantity of this rare dissociative.
Read full thread on Bluelight →
PCE's nerd page
Pharmacology, chemical data, effect profiles, and more
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Helpful Links
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