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    🧪 This is a research chemical with limited data on its long-term health effects, toxicity profile, and safe dosage ranges.

    PCE

    Aliases: Ci-400, Eticyclidine, Cyclohexamine

    Dissociative Research-chemical

    Summary TheDrug.Wiki TripSit PsychonautWiki

    PCE is a potent dissociative that causes psychosis and mania at significantly higher rates than other dissociatives. Users should avoid taking the drug multiple days in a row or in high doses. Volumetric liquid dosing is strongly recommended due to the drug's extreme potency, as most standard milligram scales cannot accurately weigh doses below 10-15 mg.

    Dose Information TheDrug.Wiki TripSit PsychonautWiki

    ROA Light Common Strong Heavy
    Oral 3-5mg 5-10mg 10-15mg 15mg+
    Insufflated 2-4mg 4-8mg 8-15mg 15mg+
    Smoked 2-4mg 4-8mg 8-12mg 12mg+
    Light Common Strong Heavy

    Onset, Duration & After-effects TheDrug.Wiki TripSit PsychonautWiki

    ROA Onset Comeup Peak Offset After Effects Total
    Oral 30-90 min 30-60 min 2-3 hrs 1-2 hrs 4-48 hrs 2-5 hrs
    Insufflated 19-60 min 30-45 min 2-3 hrs 1-2 hrs 4-48 hrs 2-5 hrs
    Smoked 30-90 min 30-60 min 2-3 hrs 1-2 hrs 4-48 hrs 2-5 hrs

    Effect Profile

    3 reports

    Scores (1–10) curated from multiple sources:

    • Effect keyword matching from PsychonautWiki catalog
    • Weighted by importance: core (×3), major (×2), minor (×1)

    Full methodology

    Dissociative 6.6
    Strong+ 7/10

    Strong dissociative depth, mania, motor impairment, and insight

    Dissociative Depth ×3
    10
    consciousness disconnection depersonalization derealization physical disconnection visual disconnection spatial disorientation +1 more
    ⚠ Mania / Compulsion ×1
    10
    mania compulsive redosing thought acceleration disinhibition stimulation
    Insight / Novel Thought ×2
    8
    conceptual thinking introspection creativity enhancement immersion enhancement
    ⚠ Motor / Sensory Impairment ×1
    10
    motor control loss physical disconnection tactile suppression numbness spatial disorientation visual disconnection
    Based on reports from:
    Bluelight Big & Dandy Thread Erowid Experience Reports PsychonautWiki PCE
    View methodology →

    Tolerance

    Build-up develops with repeated use over days to weeks
    Reset 2–4 weeks for noticeable reduction

    Tolerance Decay

    Full tolerance 1d Half tolerance 21d Baseline ~28d

    Effects Erowid

    Aggregated from 3 Erowid experience reports

    Positive Effects 2

    Empathy 100.0% 70%
    Music Enhancement 100.0% 70%

    Adverse Effects 1

    Anxiety 100.0% 70%

    Combinations TripSit

    PCE's nerd page Pharmacology, chemical data, effect profiles, and more
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    Helpful Links

    📘 Experience Reports 📖 TheDrug.Wiki 📖 TripSit 📖 Bluelight 📖 PsychonautWiki