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    Pinazepam molecular structure

    Pinazepam Stats & Data

    Domar
    PubChem
    MW308.8
    FormulaC18H13ClN2O
    LogP3.1
    IUPAC7-chloro-5-phenyl-1-prop-2-ynyl-3H-1,4-benzodiazepin-2-one
    InChIKeyMFZOSKPPVCIFMT-UHFFFAOYSA-N
    Chemical Class Benzodiazepine
    Psychoactive Class Depressant

    Pharmacology

    DrugBank

    Toxicity

    PubChem

    Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor.

    Carcinogenicity

    No indication of carcinogenicity to humans (not listed by IARC).

    Effect Profile

    Curated
    Benzodiazepine 7.6

    Strong euphoria and anxiolysis with mild sedation, low cognitive impairment

    Anxiolysis×3
    8
    Sedation / Relaxation×2
    5
    Motor / Cognitive Impairment×1
    1
    Euphoria / Mood Lift×1
    10

    Tolerance & Pharmacokinetics

    drugs.wiki

    Tolerance Decay

    Full tolerance 3d Half tolerance 37d Baseline ~60d
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